ORGANIC CHEMISTRY is a student-friendly, cutting edge introduction for chemistry, health, and the biological sciences majors. The Eighth Edition builds on unified mechanistic themes, focused problem-solving, applied pharmaceutical problems, and biological examples. Stepwise reaction mechanisms emphasize similarities among mechanisms using four traits: breaking a bond, making a new bond, adding a proton, and taking a proton away. Pull-out organic chemistry reaction roadmaps designed stepwise by chapter help students devise their own reaction pathways. Emphasizing "how-to" skills, this edition is packed with challenging synthesis problems, medicinal chemistry problems, and unique roadmap problems.