Chapter 15.2, Problem 15.3P

(a)

Interpretation Introduction

Interpretation:

The synthesis of the given each product conversion has to be identified, using the lithium diorganocopper reagent.

Concept Introduction:

Organocopper compounds: An organocopper reagents react with alkyl, alkenyl and aryl halides to give alkylated product.

It is more selective and can be acetylated with acid chlorides without concomitant attack on ketons, alkyl halides and esters.

Gilman reagent: The lithium copper (diorganocopper) reagent compound $(R_{2}CuLi)$, these reagent are very useful because unlike Grignard reagent and organolithium reagents, they react with organic halides to replace the halide group. With an alkyl (R) group.

Organometallic reagents such as organocuprate $(R_{2}CuLi)$ have a transition as their metal atom, they are used to form new carbon-carbon bonds.

• ✓  Organocuprate $(R_{2}CuLi)$ are also known as Gilman Reagent.
• ✓  It is prepared from an organolithium compound by reaction with cuprous iodide in diethyl ether or THF as follows.

(b)

Interpretation Introduction

Interpretation:

The synthesis of the given each product conversion should be identified, using the lithium diorganocopper reagent.

Concept Introduction:

Organocopper compounds: The Organocopper reagents react with alkyl, alkenyl and aryl halides to give alkylated product.

It is more selective and can be acetylated with acid chlorides without concomitant attack on ketons, alkyl halides and esters.

Gilman reagent: The lithium copper (diorganocopper) reagent compound $(R_{2}CuLi)$, these reagent are very useful because unlike Grignard reagent and organolithium reagents, they react with organic halides to replace the halide group. With an alkyl (R) group.

Organometallic reagents such as organocuprate $(R_{2}CuLi)$ have a transition as their metal atom, they are used to form new carbon-carbon bonds.

• ✓  Organocuprate $(R_{2}CuLi)$ are also known as Gilman Reagent.
• ✓  It is prepared from an organolithium compound by reaction with cuprous iodide in diethyl ether or THF as follows.