Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 3.8, Problem AQ
If the side chain of the amino add is a methyl group, the compound is referred to as alanine. What is the Cahn-Ingold-Prelog stereochemical descriptor for the chiral center in alanine?
- 1. It is a Z-stereocenter.
- 2. It is an S-stereocenter.
- 3. It is an E-stereocenter.
- 4. It is an R-stereocenter.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
I would like my graphs checked please. Do they look right? Do I have iodine and persulfate on the right axis ?
Reaction Fill-ins Part 2! Predict the
product(s) OR starting material of the
following reactions. Remember,
Hydride shifts are possible if/when a
more stable carbocation can exist
(depending on reaction mechanism)!
Put your answers in the indicated
boxes d.
d.
ง
HCI
A cylinder contains 12 L of water vapour at 150˚C and 5 atm. The temperature of the water vapour is raised to 175˚C, and the volume of the cylinder is reduced to 8.5 L. What is the final pressure of the gas in atmospheres?
assume that the gas is ideal
Chapter 3 Solutions
Organic Chemistry
Ch. 3.2 - Prob. 3.1PCh. 3.3 - Assign priorities to the groups in each set. (a)...Ch. 3.3 - Prob. 3.3PCh. 3.4 - Following are stereorepresentations for the four...Ch. 3.4 - Prob. 3.5PCh. 3.4 - Prob. 3.6PCh. 3.5 - How many stereoisomers exist for...Ch. 3.5 - How many stereoisomers exist for...Ch. 3.7 - Prob. 3.9PCh. 3.7 - Prob. 3.10P
Ch. 3.8 - If the side chain of the amino add is a methyl...Ch. 3.8 - Prob. BQCh. 3.8 - The amino acids cysteine and serine are shown....Ch. 3.8 - Prob. DQCh. 3.8 - As stated, proteins are stereochemically pure...Ch. 3.8 - As stated, proteins are stereochemically pure...Ch. 3 - Prob. 3.11PCh. 3 - One reason we can be sure that sp3-hybridized...Ch. 3 - Which compounds contain chiral centers? (a)...Ch. 3 - Prob. 3.15PCh. 3 - Prob. 3.16PCh. 3 - Prob. 3.17PCh. 3 - Mark each chiral center in the following molecules...Ch. 3 - Prob. 3.19PCh. 3 - Assign priorities to the groups in each set. (a) H...Ch. 3 - Following are structural formulas for the...Ch. 3 - Following is a staggered conformation for one of...Ch. 3 - Prob. 3.23PCh. 3 - When oxaloacetic acid and acetyl-coenzyme A...Ch. 3 - Prob. 3.25PCh. 3 - Mark each chiral center in the following molecules...Ch. 3 - Prob. 3.27PCh. 3 - Prob. 3.28PCh. 3 - Prob. 3.29PCh. 3 - Prob. 3.30PCh. 3 - Which of the following are meso compounds?Ch. 3 - Prob. 3.32PCh. 3 - Prob. 3.33PCh. 3 - Which of the following compounds are chiral?...Ch. 3 - Prob. 3.35PCh. 3 - Prob. 3.36PCh. 3 - Prob. 3.37PCh. 3 - The chiral catalyst (R)-BINAP-Ru is used to...Ch. 3 - Prob. 3.39P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- On the next page is an LC separation of the parabens found in baby wash. Parabens are suspected in a link to breast cancer therefore an accurate way to quantitate them is desired. a. In the chromatogram, estimate k' for ethyl paraben. Clearly indicate what values you used for all the terms in your calculation. b. Is this a "good" value for a capacity factor? Explain. c. What is the resolution between n-Propyl paraben and n-Butyl paraben? Again, indicate clearly what values you used in your calculation. MAU | Methyl paraben 40 20 0 -2 Ethyl paraben n-Propyl paraben n-Butyl paraben App ID 22925 6 8 minarrow_forwardd. In Figure 4, each stationary phase shows some negative correlation between plate count and retention factor. In other words, as k' increases, N decreases. Explain this relationship between k' and N. Plate Count (N) 4000 3500 2500 2000 1500 1000 Figure 4. Column efficiency (N) vs retention factor (k') for 22 nonionizable solutes on FMS (red), PGC (black), and COZ (green). 3000 Eluent compositions (acetonitrile/water, A/W) were adjusted to obtain k' less than 15, which was achieved for most solutes as follows: FMS (30/70 A/W), PGC (60/40), COZ (80/20). Slightly different compositions were used for the most highly retained solutes. All columns were 50 mm × 4.6 mm id and packed with 5 um particles, except for COZ, which was packed with 3 um particles. All other chromatographic conditions were constant: column length 5 cm, column j.§. 4.6 mm, flow rate 2 mL/min, column temperature 40 °C, and injection volume 0.5 μL Log(k'x/K'ethylbenzene) FMS 1.5 1.0 0.5 0.0 ཐྭ ཋ ཤྩ བྷྲ ; 500 0 5 10…arrow_forwardf. Predict how the van Deemter curve in Figure 7 would change if the temperature were raised from 40 °C to 55 °C. Figure 7. van Desmter curves in reduced coordinates for four nitroalkane homologues (nitropropane, black; nitrobutane, red; nitropentane, blue; and nitrohexane, green) separated on the FMS phase. Chromatographic conditions: column dimensions 50 mm × 4.6 mm id, eluent 30/70 ACN/water, flow rates 0.2-5.0 mL/min, injection volume 0.5 and column temperature 40 °C. No corrections to the plate heights have been made to account for extracolumn dispersion. Reduced Plate Height (h) ° 20 40 60 Reduced Velocity (v) 8. (2) A water sample is analyzed for traces of benzene using headspace analysis. The sample and standard are spiked with a fixed amount of toluene as an internal standard. The following data are obtained: Ppb benzene Peak area benzene Peak area toluene 10.0 252 376 Sample 533 368 What is the concentration of benzene in the sample?arrow_forward
- Liquid chromatography has been used to track the concentration of remdesivir (a broad-spectrum antiviral drug, structure shown at right) in COVID patients undergoing experimental treatments. Intensity The authors provide the following details regarding standard solutions preparation: HN CN HO OH NH2 Remdesivir (RDV) stock solution (5000 µg/mL) was prepared by dissolving RDV drug powder using the mixture of DMSO: MeOH (30:70 v/v). The RDV working standard solutions for calibration and quality controls were prepared using methanol in concentrations of 100, 10, 1, 0.1, 0.01 µg/mL. 1, 2.5, 5, 7.5, 10, 25, 50, 75, 100, 250, 500, 1000, and 5000 ng/mL sample solutions were prepared freshly by spiking calibration standard solutions into the blank human plasma samples for method calibration. a) What type of calibration method is being described? Why do you think the authors chose this method as opposed to another? b) Based on the details provided in part a, describe an appropriate method blank…arrow_forwardRecent advancements in liquid chromatography include the development of ultrahigh pressure liquid chromatography (UHPLC) and an increased use of capillary columns that had previously only been used with gas chromatography. Both of these advances have made the development of portable LC systems possible. For example, Axcend Corp. makes a portable system that uses a capillary column with an internal diameter of 150-μm-that is packed with 1.7-um stationary phase particles. In contrast, a traditional LC column has a 4.6 mm internal diameter and utilizes 5-um stationary phase particles. a) Explain one advantage that is afforded by the use of a capillary column in liquid chromatographic separation. Explain one disadvantage of capillary columns. b) Explain how the use of smaller stationary phase particles can improve the resolution of a separation. Include any relevant equations that support your explanation. c) A scientist at Rowan University is using the Axcend LC to conduct analyses of F…arrow_forwardThis paper describes the use of fullerene molecules, also known as buckyballs, as a stationary phase for liquid chromatography. The performance of the fullerene-modified stationary phase (FMS) is compared to that of a more common C18 stationary phase and to two other carbon-based stationary phases, PGC and COZ. A. 10A OM B. - Figure 1. Idealized drawing of the cross-section of a pore inside a silica particle, showing the relative densities of aminopropylsilyl (red/green) and fullerene (blue) groups: (A) full cross- section; (B) detailed view of covalent bonding of fullerene to the silica surface. Surface densities of silyl and fullerene groups were inferred from elemental composition results obtained at each stage of the synthesis (see Table 1). Absorbance (mAU, 220 nm) 700 600 500 400 300 200 100 a. Define selectivity, a, with words and an equation. b. Explain how the choice of stationary phase affects selectivity. c. Calculate the resolution of the nitrobenzene and toluene peaks in…arrow_forward
- Normalized Intensity (a. u.) 0.5 1.0 A 3D-printed GC column (shown below) was created for use with "micro" gas chromatography applications. To prove its utility, it was used to separate a mixture of alkanes (C9-C18, C22, C24). For the separation shown below, the column temperature was ramped from 40 °C to 250 °C at a rate of 30 °C per minute. (a) 9 10 = 1 mm 12 13 15 22 0.0 0 100 200 300 400 Time (sec) a) What detector would you use for this analysis? Justify your selection. b) Explain how the chromatogram would change if the separation was run isothermally. c) Explain how the chromatogram would change if the temperature ramp were increased to 50 °C per minute.arrow_forwardDevise a synthesis of each compound from the indicated starting material. You may also use any organic compounds with one or two carbons and any needed inorganic reagents. a. Brarrow_forwardPlease help me with #2b & #3 using the data.arrow_forward
- Heparin is used as an anti-coagulant. A risk of heparin use is thrombocytopenia, or low platelet count. This risk is minimized with the use of low molecular weight heparins (LMWH), therefore it is desirable to separate LMWH from higher molecular weight heparins. The method of choice to do this is molecular exclusion chromatography. Below is a chromatogram from a molecular exclusion chromatographic run. Peaks ranging from A to J are clearly distinguishable. The heparin mixture that was analyzed had anywhere from 6 to 30 repeat units of monomer (where the heparin with 30 repeat units would be roughly five times the size of the heparin with six repeat units). a. Which letter most likely represents the peak with 6 repeat units given these heparin polymers were separated with molecular exclusion chromatography? b. Explain your reasoning describing the mechanism of retention in molecular exclusion chromatography. 100 80 60 60 Relative Abundance 40 40 E GH 20 20 B A 36 38 40 42 44 46 48 50 50…arrow_forwardHELP NOW PLEASE ! URGENT!arrow_forwardHELP NOW PLEASE ! URGENT!arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning
General, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning
Organic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,
Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
Macroscale and Microscale Organic ExperimentsChemistryISBN:9781305577190Author:Kenneth L. Williamson, Katherine M. MastersPublisher:Brooks Cole
Organic Chemistry
Chemistry
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:Cengage Learning
General, Organic, and Biological Chemistry
Chemistry
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:Cengage Learning
Organic And Biological Chemistry
Chemistry
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:Cengage Learning,
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Macroscale and Microscale Organic Experiments
Chemistry
ISBN:9781305577190
Author:Kenneth L. Williamson, Katherine M. Masters
Publisher:Brooks Cole
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY