(a)
Interpretation:
The product of the base-catalysed aldol reaction of the given compound has to be predicted.
Concept introduction:
Aldol reaction is an addition reaction of
(b)
Interpretation:
The product of the base-catalysed aldol reaction of the given compound has to be predicted.
Concept introduction:
Aldol reaction is an addition reaction of aldehydes and ketones. Aldol reaction is a reversible reaction and occurs in the presence of a strong base like sodium hydroxide. One molecule (aldehyde or ketone) acts a nucleophile and attacks the electrophilic carbon center of the other molecule to give the addition product. The product is named
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Chapter 19 Solutions
Organic Chemistry
- Give the structure of the major nrganic reactant(x) in aldol, aldol condensation or Claisen condensation. a) b) OEIarrow_forwardDraw the product formed when phenylacetic acid (C6H5CH2COOH) istreated with following reagent. With some reagents, no reaction occurs. [1] NaOH; [2] CH3COClarrow_forwardI need help listing the appropriate starting materials for each aldol reaction.arrow_forward
- a) Give the mechanism for the following regioselectie allylation reaction. Answer the question with the arrow: b) Give both structures and IUPAC names of the reactants for the compound below formed via a crossed aldol reaction with KOH as promotor. Explain why only one product is formed.arrow_forwardShow how you would synthesize octanal from each compound. You may use any necessary reagents.(a) octan-1-olarrow_forwardDraw the product formed from acetaldehyde using (OH, H2O). (Aldol reaction & dehydrationarrow_forward
- Draw the product formed when phenylacetic acid (C6H5CH2COOH) istreated with following reagent. With some reagents, no reaction occurs. SOCl2arrow_forwardVanillin has an acidic OH and an electrophilic aldehyde group that could conceivably react with sodiumhydroxide. However, in the aldol reaction, you added the NaOH directly to the solution of vanillin andacetone, rather than pre-treating acetone with base. Why could you do this successfully? a) NaOH is a weak base and a weak nucleophile.b) The reaction of NaOH with phenol OH groups and aromatic aldehydes is reversible, and thereaction is driven to the most stable product.c) The aldehyde in vanillin is unreactive towards nucleophiles.d) The NaOH is not soluble in the reactionarrow_forwardDraw the product formed form acetaldehyde using -OH, H2O. (Aldol reaction &dehydration)arrow_forward
- Draw the products formed when p-methylaniline (p-CH3C6H4NH2) istreated with following reagent. HClarrow_forwardPropose a mechanism for the reaction of benzyl acetate with methylamine. Label theattacking nucleophile and the leaving group, and draw the transition state in which theleaving group leaves.arrow_forward2. Cinnamaldehyde is used as a flavoring agent in cinnamon candies. Synthesize cinnamaldehyde by cross aldol condensation followed by dehydration.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning