A reaction sequence for the synthesis of the given compound has to be proposed. Concept Introduction: Reformatsky reaction: It states that the treatment of an α − haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β − hydroxyester.

Question

The following substances can be prepared by a nucleophilic addition reaction between an aldehyde or ketoneand a nucleophile. Identify the reactants from which they were prepared. If the substance is an acetal, identifythe carbonyl compound and the alcohol; if it is an imine or enamine, identify the carbonyl compound and theamine. You do not have to consider stereochemistry. In cases where there is more than one answer, just giveone. Use Grignard reagents when an organometallic reagent is required. Draw the Grignard reagent as acovalent magnesium bromide.

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 19, Problem 19.37P

(a)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(b)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(c)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

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The following substances can be prepared by a nucleophilic addition reaction between an aldehyde or ketoneand a nucleophile. Identify the reactants from which they were prepared. If the substance is an acetal, identifythe carbonyl compound and the alcohol; if it is an imine or enamine, identify the carbonyl compound and theamine. You do not have to consider stereochemistry. In cases where there is more than one answer, just giveone. Use Grignard reagents when an organometallic reagent is required. Draw the Grignard reagent as acovalent magnesium bromide.

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What is the structure of the compound formed when 5-nitro-2-furaldehyde reacts with 4-cyanophenyl hydrazine hydrochloride?

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 19, Problem 19.37P

(a)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(b)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(c)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

Expert Solution & Answer

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Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 19, Problem 19.37P

(a)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(b)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

(c)

Interpretation Introduction

Interpretation:

A reaction sequence for the synthesis of the given compound has to be proposed.

Concept Introduction:

Reformatsky reaction:

It states that the treatment of an α− haloester with zinc metal in the presence of an aldehyde or a ketone followed by hydrolysis in aqueous acid results in formation of a β− hydroxyester.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 19, Problem 19.37P

(a)

Interpretation Introduction