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- One frequently used method for preparing methyl esters is by reaction of carboxylic acids with diazomethane, CH2N2. The reaction occurs in two steps: (l) protonation of diazomethane by the carboxylic acid to yield methyldiazonium ion, CH3N2+, plus a carboxylate ion; and (2) reaction of the carboxylate ion with CH3N2+. (a) Draw two resonance structures of diazomethane, and account for step 1. (b) What kind of reaction occurs in step 2?Ketones and aldehydes react with sodium acetylide (the sodium salt of acetylene) to give alcohols, as shown in the following example: R₁ OH 1. HC=C: Na* + R₂ Rí R2 2. H3O+ HC Draw the structure of the major reaction product when the following compound reacts with sodium acetylide, assuming that the reaction takes preferentially from the Re face of the carbonyl group. • Use the wedge/hash bond tools to indicate stereochemistry where it exists. • You do not have to explicitly draw H atoms. •If a group is achiral, do not use wedged or hashed bonds on it. E CH3 H3CPredict the product for the following Sn2 reactions.
- Provide synthetic routes for the preparation of the starting materials of azo dye Alizarine Yellow R starting from benzene O₂N -NEN OH CO₂HPredict the major products of the following reactions. Please show mechanisms in detail.What is the major organic product obtained from the following reaction? CH3 K2Cr2O7 CH₂OH CHO 2 COOH OH 6=6556 1 3 4 2



