The synthesis for the given intermediate from the compound A has to be proposed. Concept introduction: Enamine: An enamine is a compound where the lone pair of electrons in the nitrogen atom of C − N bond gets delocalized by the presence of nearby C = C bond. It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule. Stork Enamine reaction: In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

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Answer 1

Question

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

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Answer 2

Question

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

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Answer 3

Question

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

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Answer 4

Question

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

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Answer 5

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

Answer 6

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

Answer 7

Chapter 19, Problem 19.42P

Interpretation Introduction

Interpretation:

The synthesis for the given intermediate from the compound A has to be proposed.

Concept introduction:

Enamine:

An enamine is a compound where the lone pair of electrons in the nitrogen atom of C−N bond gets delocalized by the presence of nearby C=C bond.

It is formed by the reaction of a ketone or aldehyde and a secondary amine under acidic conditions with the elimination of water molecule.

Stork Enamine reaction:

In the reaction, enamine formation from a ketone or aldehyde occurs. Then the addition of this enamine to an alkyl halide or ketone is done. The alkylated enamine is hydrolysed to get starting ketone or aldehyde.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 19.2 - Prob. 19.1P Ch. 19.2 - Prob. 19.2P Ch. 19.2 - Prob. 19.3P Ch. 19.3 - Prob. 19.4P Ch. 19.3 - Prob. 19.5P Ch. 19.3 - Prob. 19.6P Ch. 19.5 - Prob. 19.7P Ch. 19.5 - Prob. 19.8P Ch. 19.5 - Prob. 19.9P Ch. 19.6 - Prob. 19.10P

Solution Summary: The author explains that the synthesis for the given intermediate from the compound A has to be proposed.

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Chapter 19 Solutions