
Concept explainers
Interpretation :
The similarly between a peptide bond and an ester formed from an acid and alcohol must be explained.
Concept Introduction :
Both esterification and peptide bond formation are condensation reaction in which water is eliminated.

Answer to Problem 6E
In peptide bond formation, an amide is produced from acid and
Explanation of Solution
The peptide bond formation and esterification reaction is represented as follows:
The peptide bond (amide) and ester bond are shown in red.
In both cases, the reaction is condensation as water is removed.
In the peptide bond formation, -CONH bond is formed and in the esterification reaction −COO bond is formed.
Forming a peptide bond is similar to forming an ester from acid and alcohol.
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