Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 8, Problem 23RQ
Summary Introduction

To review:

The effects of the following molecules on gluconeogenesis:

a. Lactate

b. ATP (adenosine triphosphate)

c. Pyruvate

d. Glycerol

e. AMP (adenosine monophosphate)

f. Acetyl Co-A (acetyl coenzyme A)

Introduction:

The process by which new molecules of glucose are formed from the noncarbohydrate molecule, such aspyruvate, glycerol, lactate, and alpha keto acids, is called gluconeogenesis. The process of gluconeogenesis takes place in the liver and kidneysunder certain conditions.

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QUESTION 2 Consider the chemical transformation in the reaction shown below. Select the fermentation or gluconeogenesis enzyme that catalyzes the most similar type of transformation. NAD H NAD O: HO Pyruvate decarboxylase Lactate dehydrogenase/alcohol dehydrogenase O Pyruvate carboxylase O Phosphoenolpyruvate carboxykinase (PEPCK) Fructose 1,6-bisphosphatase/glucose 6-phosphatase
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Chapter 8 Solutions

Biochemistry: The Molecular Basis of Life

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