Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 8, Problem 4Q
Summary Introduction

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The accountable reason behind the cycling of gluconeogenesis and glycolysis, resulting in the condition of malignant hyperthermia in an individual.

Introduction:

The medical condition that arises as a result of a reaction, in response to the administration of certain medication, say general anesthetics, is referred to as malignant hyperthermia. It causes rigidity in the muscles, a high fever, and increases the heart rate.

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Background Freezing isn't the only challenge in cryopreservation - thawing can be just as difficult. A microwave oven seems like a nice solution, since it deposits energy quickly and microwaves are non-ionizing radiation (they do not cause DNA mutation). However, water absorbs microwaves more effectively than ice does, meaning that the portion of an organ that has already melted will get warmer at a higher rate than the remaining ice – the opposite of what we want! - The transmission of radiation through a weakly absorbing material such as ice or water can be modeled by Beer's law, which assumes that the rate of absorption at a depth x is proportional to the local radiation intensity I(x) times an absorption coefficient, which is often written as μ or a or just µ). Noting that absorption decreases the intensity, we can write a differential equation a Solving the differential equation with the boundary condition on the surface being gives the relationship For a standard microwave oven…

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Biochemistry: The Molecular Basis of Life

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