
To review:
Definition of the following biological terminologies:
a. Biomolecule
b. Macromolecule
c. Enzyme
d.
e. Homeostasis
Introduction:
A living organism is able to sustain and regulate its biological functions due to variety and diversity of

Explanation of Solution
Following are the definitions for the biological terminologies:
a. Biomolecule:
These are the molecules found in the living organisms and are vital for the functioning, growth, development, and regulation of the living system. These contain macromolecules like proteins, carbohydrates, fats (lipids) and nucleic acids. Biomolecules consist of inorganic and organic components: inorganic component consist of water, ions like (Na+), potassium (K+), magnesium (Mg2+), and calcium (Ca2+), and organic component consist carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur.
b. Macromolecule:
These are large molecules as they are comprised of thousands of atoms which makes them a complete molecule. For example, in a biological system proteins and nucleic acids are macromolecules.
c. Enzyme:
Enzyme is defined as a biological catalyst (protein molecules) enhances the rate of a
d. Metabolism:
In order to regulate and maintain life, there are various reactions which undergo within a living system. This involves the synthesis of new compounds and breakdown of other molecules. All these reactions occur within the body and are referred to as a metabolic reaction and phenomenon is called metabolism.
e. Homeostasis:
A physiological process in which equilibrium condition is maintained or constant internal environment is maintained within a living organism.
Biomolecules, macromolecules, enzymes are the biological molecules while metabolism and homeostasis are the biological processes essential to maintain the integrity and efficiency of biological system.
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Chapter 1 Solutions
Biochemistry: The Molecular Basis of Life
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- a. Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle. (Include name of Enzymes involved) b. How many rounds of Krebs will be required to waste all Carbons of Glutamic Acid as CO2? (Show by drawing out the mechanism that occurs)arrow_forwardThe malate-aspartate shuttle allows malate to be exchanged for aspartate acrossthe inner mitochondrial membrane. (a) Describe the role of the malate-aspartate shuttle in liver cells under HIGHblood glucose conditions. Be sure to explain your answer. (b) Describe the role of the malate-aspartate shuttle in liver cells under LOW blood + glucose conditions.arrow_forward(a) Write out the net reaction, calculate ∆E ̊' for the reaction, and calculate the standard free-energy change (∆G°') for the overall oxidation/reduction reaction. (h) How many moles of ATP could theoretically be generated per mole of FADH2 oxidized by this reaction, given a ∆G ̊' of ATP synthesis of + 31 kJ/mol? How many moles of ATP could be generated per mole of FADH2 oxidized by this reaction under more typical cellular conditions (where ∆G' of ATP hydrolysis is ~ -50 kJ/mol)? Be sure to show your work and explain your answer.arrow_forward
- Indicate for the reactions below which type of enzyme and cofactor(s) (if any) would be required to catalyze each reaction shown. 1) Fru-6-P + Ery-4-P <--> GAP + Sed-7-P2) Fru-6-P + Pi <--> Fru-1,6-BP + H2O3) GTP + ADP <--> GDP + ATP4) Sed-7-P + GAP <--> Rib-5-P + Xyl-5-P5) Oxaloacetate + GTP ---> PEP + GDP + CO26) DHAP + Ery-4-P <--> Sed-1,7-BP + H2O7) Pyruvate + ATP + HCO3- ---> Oxaloacetate + ADP + Piarrow_forwardThe phosphate translocase is an inner mitochondrial membrane symporter that transports H2PO4- and H+ into the mitochondrial matrix. Phosphate is a substrate for Complex V (the ATP Synthase), the enzyme that couples the synthesis of ATP to the H+ gradient formed by the electron transport chain. (a) Bongotoxin is a hypothetical compound that inhibits the phosphate translocase of the inner mitochondrial membrane. Explain why electron transport from NADH to O2 stops when bongotoxin is added to mitochondria (i.e., why do electrons stop flowing through the electron transport chain even with an abundance of NADH and O 2 present). What effect will the addition of the weak acid dinitrophenol (DNP) to the cytosol have on electron transport in bongotoxin-inhibited mitochondria? Be sure to explain your answers. (b) How much free energy is released (in kJ) when one mole of protons flows from the mitochondrial inner membrane space (IMS) to the mitochondrial matrix when the [H+ ] in the IMS is 7.9 x…arrow_forwardWhen TMPD/ascorbate is added to mitochondria as a source of electrons (TMPD/ascorbate reduce cytochrome c directly) oxygen is reduced to H2O by the electron transport chain (ETC).(a) Approximately how many ATPs would result per O2 consumed when electrons come from TMPD/ascorbate? (b) If dinitrophenol (DNP) is added to the mitochondria in (a) above, what effect would DNP have on the yield of ATPs per O2 reduced from TMPD/ascorbate electrons?arrow_forward
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