
Concept explainers
(a)
Interpretation:
The number of cans of a regular soft drink that should be consumed by a 65 kg person in a short period of time before exceeding the lethal dose of caffeine must be calculated.
Concept Introduction :
LD50is known as lethal dose which is the dose in mg/kg required to kill the 50 % of living cells.
(a)

Answer to Problem 3E
A 65 kg person can drink 364 cans of regular soft drink in a short period of time before exceeding the lethal dose.
Explanation of Solution
Lethal dose (LD50) of caffeine is 140 mg/kg. So for a 65 kg person the amount required will be:
There are 25 mg of caffeine in a can of regular soft drink.
Number of cans of regular soft drink which will contain 9100 mg of caffeine will be:
(b)
Interpretation:
Toxicity of caffeine in moles/kg must be calculated.
Concept Introduction :
Toxicity of a substance in moles/kg means the amount of the substance required in mole per kg body weight of the living being to kill 50 % of living cells.
(b)

Answer to Problem 3E
The toxicity of caffeine is
Explanation of Solution
Molecular weight of caffeine is 194.
LD50 of caffeine is 140 mg/kg.
Moles of caffeine in 140 mg can be calculated as follows:
Chapter U4 Solutions
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