
Interpretation: The reason due to which it is necessary to take person’s weight into account when considering the correct does for a medication is to be described.
Concept introduction: To keep the public safe, health experts measure the toxicity of substances that people might be exposed to in the course of their daily routine. The most accepted measurement of toxicity is called lethal dose.

Answer to Problem C14.2RE
If the weight is more it will take more amount of same substance which can prove lethal for a person.
Explanation of Solution
Measuring toxicity related to the person’s body weight, or the amount of doses of a particular substance that can prove to be toxic. More the weight it will take more amount of same substance that can be lethal for a person.
Measuring toxicity can be challenging as the body weight of an individual can vary from 40kg to 150 kg. Thus toxicity of lethal dosage is measured per kg of body weight.
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