
Interpretation:
The relation between moles and toxicity must be explained.
Concept introduction:
Toxicity of a substance is generally expressed as LD50 value. It is given in mg/kg body weight.

Answer to Problem 1TAI
LD50 values for different substances can be converted to moles/kg unit to compare toxicity.
Explanation of Solution
Saccharin has LD50value 140 mg/kg. aspartame has LD50 value 10 mg/kg.
Both of these can be converted to moles/kg dose by dividing the mass(in g) with molecular weight to compare the toxicity.
Moles of saccharine in 140 mg is
LD50 value for saccharine is
Moles of aspartame in 10 mg is
Thus, LD50 of aspartame in moles/kg is lesser as compared to saccharine.
Chapter U4 Solutions
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