
Concept explainers
(a)
Interpretation:
The number of turns of the fatty acid biosynthetic pathway needed for the biosynthesis of a C16 saturated fatty acid from acetyl CoA molecules has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is a cyclic process to synthesize saturated fatty acid.
The different reactions that are involved in the cyclic process are:
(b)
Interpretation:
The molecules of malonyl ACP that must be formed in the biosynthesis of a C16 saturated fatty acid from acetyl CoA molecules has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is a cyclic process to synthesize saturated fatty acid.
The different reactions that are involved in the cyclic process are:
(c)
Interpretation:
The number of high-energy ATP bonds that are consumed in the biosynthesis of a C16 saturated fatty acid from acetyl CoA molecules have to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is a cyclic process to synthesize saturated fatty acid.
The different reactions that are involved in the cyclic process are:
(d)
Interpretation:
The numbers of NADPH molecules that are needed in the biosynthesis of a C16 saturated fatty acid from acetyl CoA molecules have to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is a cyclic process to synthesize saturated fatty acid.
The different reactions that are involved in the cyclic process are:

Want to see the full answer?
Check out a sample textbook solution
Chapter 25 Solutions
General, Organic, and Biological Chemistry
- What did the Cre-lox system used in the Kikuchi et al. 2010 heart regeneration experiment allow researchers to investigate? What was the purpose of the cmlc2 promoter? What is CreER and why was it used in this experiment? If constitutively active Cre was driven by the cmlc2 promoter, rather than an inducible CreER system, what color would you expect new cardiomyocytes in the regenerated area to be no matter what? Why?arrow_forwardWhat kind of organ size regulation is occurring when you graft multiple organs into a mouse and the graft weight stays the same?arrow_forwardWhat is the concept "calories consumed must equal calories burned" in regrads to nutrition?arrow_forward
- You intend to insert patched dominant negative DNA into the left half of the neural tube of a chick. 1) Which side of the neural tube would you put the positive electrode to ensure that the DNA ends up on the left side? 2) What would be the internal (within the embryo) control for this experiment? 3) How can you be sure that the electroporation method itself is not impacting the embryo? 4) What would you do to ensure that the electroporation is working? How can you tell?arrow_forwardDescribe a method to document the diffusion path and gradient of Sonic Hedgehog through the chicken embryo. If modifying the protein, what is one thing you have to consider in regards to maintaining the protein’s function?arrow_forwardThe following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.arrow_forward
- The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?arrow_forwardWhat protein is necessary for packaging acetylcholine into synaptic vesicles?arrow_forward1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningConcepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College



