To identify the oxidizing agent that is needed in step 1 of a turn of the β − oxidation pathway. Concept introduction: The β − oxidation pathway is defined as a repetitive series of four biochemical reactions in which acyl CoA is degraded to acetyl CoA by the removal of two carbon atoms at a time. NADH and FADH 2 are also produced in this pathway. An oxidizing agent oxidizes other substance and reduces itself in a chemical reaction .

Question

. Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid is located on the outside of the soluble protein but not near an active site. O-H¨ A. What type of mutation occurred? O-H B. What 2 types of chemical bonds are found in the R-groups of each amino acid? The R groups are shaded. CH2 CH2 CH2 H2N-C-COOH H2N-C-COOH 1 H Glutamic acid H Aspartic acid C. What 2 types of bonds could each R-group of each of these amino acids form with other molecules? D. Consider the chemical properties of the two amino acids and the location of the amino acid in the protein. Explain what effect this mutation will have on this protein's function and why.

Answer 1

Question

Chapter 25, Problem 25.27EP

Interpretation Introduction

Interpretation: To identify the oxidizing agent that is needed in step 1 of a turn of the β−oxidation pathway.

Concept introduction: The β−oxidation pathway is defined as a repetitive series of four biochemical reactions in which acyl CoA is degraded to acetyl CoA by the removal of two carbon atoms at a time. NADH and FADH2 are also produced in this pathway.

An oxidizing agent oxidizes other substance and reduces itself in a chemical reaction.

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