The configuration of the β-hydroxyacyl CoA formed by hydration during a turn of the β-oxidation pathway has to be determined. Concept introduction: Theβ-oxidation pathway is defined as a repetitive series of four biochemical reactions in which acyl CoA is degraded to acetyl CoA by the removal of two carbon atoms at a time. NADH and FADH 2 are also produced in this pathway. The configuration is defined as the spatial arrangement of atoms or groups in a molecule. The stereoisomers have the same molecular formula but a different arrangement of atoms in the three-dimensional space. The D and L notation describes the configurational stereochemistry of molecules. In the D isomer, the hydroxy (-OH) group present on the farthest chiral centre from the carbonyl is present on the right side while in the L isomer, the hydroxy group present on the farthest chiral centre from the carbonyl is present on the left side.

Question

Want to see the full answer?

Answer 1

Question

Chapter 14, Problem 14.32EP

Interpretation Introduction

Interpretation:

The configuration of the β-hydroxyacyl CoA formed by hydration during a turn of the β-oxidation pathway has to be determined.

Concept introduction:

Theβ-oxidation pathway is defined as a repetitive series of four biochemical reactions in which acyl CoA is degraded to acetyl CoA by the removal of two carbon atoms at a time. NADH and FADH₂ are also produced in this pathway.

The configuration is defined as the spatial arrangement of atoms or groups in a molecule. The stereoisomers have the same molecular formula but a different arrangement of atoms in the three-dimensional space. The D and L notation describes the configurational stereochemistry of molecules.

In the D isomer, the hydroxy (-OH) group present on the farthest chiral centre from the carbonyl is present on the right side while in the L isomer, the hydroxy group present on the farthest chiral centre from the carbonyl is present on the left side.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

The data for the potential difference of a battery and its temperature are given in the table. Calculate the entropy change in J mol-1 K-1 (indicate the formulas used).Data: F = 96485 C mol-1

In a cell, the change in entropy (AS) can be calculated from the slope of the E° vs 1/T graph. The slope is equal to -AS/R, where R is the gas constant. Is this correct?

Using the Arrhenius equation, it is possible to establish the relationship between the rate constant (k) of a chemical reaction and the temperature (T), in Kelvin (K), the universal gas constant (R), the pre-exponential factor (A) and the activation energy (Ea). This equation is widely applied in studies of chemical kinetics, and is also widely used to determine the activation energy of reactions. In this context, the following graph shows the variation of the rate constant with the inverse of the absolute temperature, for a given chemical reaction that obeys the Arrhenius equation. Based on the analysis of this graph and the concepts acquired about the kinetics of chemical reactions, analyze the following statements: I. The activation energy (Ea) varies with the temperature of the system. II. The activation energy (Ea) varies with the concentration of the reactants. III. The rate constant (K) varies proportionally with temperature. IV. The value of the…