Either polynucleotide synthesized from 3’ to 5’end or 5’ to 3’ end has to be interpreted. Concept Introduction: Composition of nucleic acid : Nucleic acid is a polymer of nucleotides. Each nucleotide has three parts: a sugar, a nitrogenous base, and a phosphate group. Sugar: In both DNA and RNA, sugar portion is found. In DNA, the sugar is D-ribose, where at 2’hydroxyl group is absent and in RNA, the hydroxyl group is present at 2’. Nitrogenous bases: Five types of nitrogenous bases (has unique one-letter code A, G, T, U, and C) are derived from two parent compounds called purine and pyrimidine. The purine derivatives are Adenine and Guanine, which are two fused nitrogen containing rings. The pyrimidine derivatives are Thymine, Cytosine and Uracil, which are nitrogen containing six-membered ring. Adenine, Guanine, Thymine, and Cytosine are the nitrogenous bases present in DNA. Adenine, Guanine, Cytosine and Uracil are the nitrogenous bases present in RNA. Numbering the atoms in sugar and base rings: In order to distinguish the atoms in the sugar of a nucleoside and atoms of a base ring, numbers without prime is used for atoms in the base ring and numbers with prime used for the atoms in the sugar ring.

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Chapter 26, Problem 26.39AP

Interpretation Introduction

Interpretation:

Either polynucleotide synthesized from 3’ to 5’end or 5’ to 3’ end has to be interpreted.

Concept Introduction:

Composition of nucleic acid: Nucleic acid is a polymer of nucleotides. Each nucleotide has three parts: a sugar, a nitrogenous base, and a phosphate group.

Sugar: In both DNA and RNA, sugar portion is found. In DNA, the sugar is D-ribose, where at 2’hydroxyl group is absent and in RNA, the hydroxyl group is present at 2’.

Nitrogenous bases: Five types of nitrogenous bases (has unique one-letter code A, G, T, U, and C) are derived from two parent compounds called purine and pyrimidine. The purine derivatives are Adenine and Guanine, which are two fused nitrogen containing rings. The pyrimidine derivatives are Thymine, Cytosine and Uracil, which are nitrogen containing six-membered ring. Adenine, Guanine, Thymine, and Cytosine are the nitrogenous bases present in DNA. Adenine, Guanine, Cytosine and Uracil are the nitrogenous bases present in RNA.

Numbering the atoms in sugar and base rings:

In order to distinguish the atoms in the sugar of a nucleoside and atoms of a base ring, numbers without prime is used for atoms in the base ring and numbers with prime used for the atoms in the sugar ring.

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