Chapter 25, Problem 25.90EP

(a)

Interpretation Introduction

Interpretation:

The step in which the second hydrogenation reaction occurs in the first cycle of the lipogenesis pathway has to be identified.

Concept introduction:

Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.

A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.

(b)

Interpretation Introduction

Interpretation:

The step in which condensation reaction occurs in the first cycle of the lipogenesis pathway has to be identified.

Concept introduction:

Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.

A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.

(c)

Interpretation Introduction

Interpretation:

The step in which acetoacetyl ACP is used as a reactant in the first cycle of the lipogenesis pathway has to be identified.

Concept introduction:

Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.

A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.

(d)

Interpretation Introduction

Interpretation:

The step in which the production of crotonyl ACP occurs in the first cycle of the lipogenesis pathway has to be identified.

Concept introduction:

Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.

A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.