TOH1 protein is typically expressed at the same level in kidney and stomach cells and is essential to appropriate function of both organs.  TOH disorder is a disorder where no detectable TOH1 protein is present in kidney cells due to a mutation in the promoter leading to no transcription.  No other organs are affected in TOH disorder.  You used microarray analysis to examine cells from kidney and stomach cells from the same individual with TOH disorder.  You labeled the cDNA from the affected kidney cells with red fluorescent nucleotides, and you labeled the cDNA from the unaffected stomach cells with green fluorescent nucleotides.  After you mixed the cDNAs and allowed for hybridization, what color would you expect to see for the spot for the TOH1 gene when you analyze the microarray data? a) Red b) Green c) Black d) Yellow

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A:

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.