You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of the BMP5 enhancer found in diseased osteoblasts. You put this reporter transgene into a normal, healthy osteoblast. If the healthy osteoblast with your GFP-reporter transgene DOES turn green (GFP is expressed), what is one possible genetic reason that BMP5 is not being expressed in people with this disease?  Explain your answer

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You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of the BMP5 enhancer found in diseased osteoblasts. You put this reporter transgene into a normal, healthy osteoblast.

If the healthy osteoblast with your GFP-reporter transgene DOES turn green (GFP is expressed), what is one possible genetic reason that BMP5 is not being expressed in people with this disease?  Explain your answer

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