Relative Relative H3/H4 Acetylation Relative H3 Acetylation H4 Acetylation DON -4Kb -3Kb -2Kb -1Kb +1 Insulin You are studying histone modification at the insulin gene in cell types that express insulin (3 & A 4) compared to cell types that do not express insulin (1 & 2). Enhancer Promoter 20 15 10 5 Discuss with your pod: In which cell type(s) is H3 acetylation highest? In which cell type(s) is H4 acetylation highest? 3. Is histone acetylation the same at the enhancer and promoter? 4. Based on the data, which histone modification is most 1. В 20 2. 15 10 5 C important for activating insulin gene expression?

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Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.