The expression of this inhibitor of G2 to M Phase of the cell cycle progression will be significantly upregulated in a muscle cell that has had a drastic drop in insulin stimulation due to glucose and amino acids withdrawal; Group of answer choices ARF CiP/KiP-p21 CiP/KiP-p27 p57

Q: for question 1, choose wheater each choice is either tumor suppressor or proto oncogene\ for…

A: Proto-oncogenes and tumor suppressor genes are two types of genes that play important roles in the…

Q: Relative Relative H3/H4 Acetylation Relative H3 Acetylation H4 Acetylation DON -4Kb -3Kb -2Kb -1Kb…

A: DNA is responsible for carrying genetic information in cells. DNA is packaged into condensed form…

Q: QUESTION 8 Which of the following is true of the RAS proto-oncogene? O Mutations involving RAS are…

A: Mutations are alterations in the DNA sequence of an organism. Small changes, such as adding or…

Q: The gene that encodes the enzyme called tyrosine hydroxylase is known to be activated by the CREB…

A: The central dogma of molecular biology explains the flow of genetic information through the…

Q: Degradation of which protein is one of the triggers for the intiation of Mphase of the cell cycle…

A: There are various cheakpoints in cell cycle which have to be passed by the cell during its division…

Q: Protein mutations that result in a hyperproliferative (sustained proliferative…

A: Protein mutations that lead to hyperproliferative cell phenotypes are often classified as oncogenic…

Q: The GA(T>C)A mutation in the Duffy promoter impacted expression of Duffy in the following cell…

A: The promoter is the region where the RNA polymerase binds during the transcription i.e. synthesis of…

Q: Indicate whether each of the following statements related is likely to be true or false. [ Select 1…

A: Proper regulation of the cell cycle is essential for maintaining tissue homeostasis, ensuring proper…

Q: a. A typical cellular response of a mammary epithelial cell to EGF signal is proliferation. the Kd…

A: Proliferation is the cellular response.

Q: PINK LAMP2A BCL2 ATF6 [Choose] [Choose] promoting UPR promoting apoptosis inhibiting autophagy…

A: PINK1 gene gives instruction to form PINK 1 protein. Highest level of this protein is found in…

Q: Given the following scenario, indicate if this will ‘promote’ or ‘prevent’ cancer development: An…

A: Bcl-2, or B-cell lymphoma 2, is a protein that plays a crucial role in regulating apoptosis…

Q: Explain insulin's signal transduction pathways and trace the pathway of cell signaling from the cell…

A: Insulin is a peptide hormone that is secreted by the b cells in pancreas. It act through a receptor…

Q: Expression of S-phase genes is activated when P16 inactive or absent P16 active Cdk4 inactive

A: The cell cycle is regulated by cyclins(regulatory proteins present in varying concentrations during…

Q: Activation of p53 during cellular stress will generally Select one: o a. Increase transcription of…

A: P553 is a tumor suppressor gene.

Q: The yeast cohesin subunit Scc1, which is essen-tial for sister-chromatid cohesion, can be…

A: The foundation of sister chromatid cohesion is the cycle by which chromatin-related cohesin protein…

Q: Define about Several types of cellular stress events bring about rapidincreases in the nuclear…

A: The p53 is also known as the guardian of the genome. It is a tumor suppressor gene. The function of…

Q: A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies…

A: A gene that produces a protein that is essential for regulating cell division and death and is…

Q: GAP protien mutation from Arg 789 to alanine constituvely activate the MAPK pathway by preventing…

A: Cell growth and cell division are essential for the development of an organism. A cell before any…

Q: You are studying cancer progression in mice. Your results show the following pathway in which two…

A: From the given data the observations made are: The experiment is conducted in a nutrient-enriched…

Q: cells undergo programmed cell death. Write out the pathway(s), noting the changes (e.g.,…

A: Cell division is a fundamental process in living organisms that allows for growth and tissue repair.…

Q: Cell division is carefully regulated and coordinated in eukaryotic cells by protein kinases that…

A: The division of all cells must be carefully regulated and coordinated with both cell growth and DNA…

Q: Scientists have identified overexpression of Na+/K+ ATPases in several types of cancers plorectal…

A: It is given that we have to design a drug which is preventing the overexpression of the Na+/K+…

Q: Protein P, normally stimulates apoptosis or cell death when activated. Consider a cell with a…

A: The construction of this question gives us an  information about the nature of protein P, P when…

Q: How IRS activate PI3K mediated glucose uptake?

A: The insulin receptor is a hetero-tetrameric protein of the membrane expressed in two identical…

Q: In an E. coli mutant, beta galactosidase and permease are expressed at high levels when both glucose…

A: In normal condition, when lactose level is high and glucose level is low, galactosidase and permease…

Q: Chromosomal translocation can result in cells expressing a fusion protein with uncontrolled receptor…

A: The correct answer is Tel/PDGFR

Q: Specific control points that are sensitive to extracellular conditions regulate G1-S transition in…

A: Eukaryotic cells has nucleus with proper nuclear membrane, cell membrane and other membrane bound…

Q: In many breast cancers, ER (alpha) activation by estrogens is generally considered responsible for…

A: In breast cancers, the activation of estrogen receptor alpha (ERα) by estrogens is often associated…

Q: The Wnt planar polarity signaling pathway nor-mally ensures that each wing cell in Drosophila has a…

A: Gene expression is the phenomenon in which the gene expresses itself in the form of functional…

Q: In a patient with a constitutively active receptor tyrosine kinase that increases the activity of…

A: Tyrosine kinase is a type of enzyme that plays a crucial role in cell signaling pathways by adding a…

Q: The Human papillomavirus (HPV) has been linked to an increased risk of cervical cancer. The HPV E6…

A: P63 genes provide instructions for the production of a tumor protein p63 (also known as p63). The…

Q: Cells of random sizes (some very small) are formed after cell division Normal sized cells are formed…

A: This ftsz protein that stands for filamentous temperature-sensitive protein Z plays a very important…

Q: All but which of the following best explains the advantage of cancer cells expressing PKM2 over…

A: Cancer refers to abnormal growth of the cells and this they will divide uncontrollably. The cancer…

Q: "Schematic outline of melanogenesis. UVR stimulates the expression of POMC by keratinocytes. The…

A: Melanogenesis is the chemical pathway through which natural pigments known to be melanin pigments…

Q: Signaling pathways often require receptor dimers to become active. What would be an advantage of the…

A: Most receptors dimerize during their association with their ligands. This dimerization provides them…

Q: The P63 and P53 have similar functionalities in the cell, however, p53 is rarely associated directly…

A: Tumor protein 63 (p63) could also be a transcription factor of the p53 gene family encoded by the…

Q: This TSG targets beta-catenin for degradation and inhibits the Wnt signaling pathway but when it is…

A: These are genes that inhibits cell division of the cell, repair mistakes in DNA or control apoptosis…

Q: Given what you have learned about tumor suppressors and proto-oncogenes, predict whether the…

A: Introduction :- Oncogenes are genes that, when mutated or overexpressed, can cause cells to grow and…

Q: A tumor suppressor gene (TSG) codes for a protein that is part of the system that regulates cell…

A: Normal genes that halt cell division or fix DNA errors are known as tumor suppressor genes. Such…

Q: Describe at least two Cdk regulation check points during the cell cycle, Describe how that Step is…

A: cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends…

Q: that binds Fsh3 is a receptor tyrosine kinase (RTK) and there are numerous fish tumor cell lines…

A: Answer. Enzyme-linked receptors are a second major type of cell surface receptors. Like…

Q: You established two cell lines (Cell line X and Cell line Y) from colon cancer patients and both of…

A: Wnt Signalling Pathways Are A Collection Of Signal Transduction Pathways That Start With Proteins…

Q: Isothiocyanates are compounds found in vegetables such as broccoli. Such compounds have been shown…

A: The cervix is the lowermost section of the uterus and when a malignant tumour appear here, it’s…