Growth Factor (GF-signal) Activation of GF Receptor (RTK-receptor) To cause Cell proliferation/cell division (Response) Plasma membrane Grb2 (Ras GEF) (adapter) Raf MAPKKK Mek MAPKK Activation of target genes that stimulate ertion Erk MAPK You have a skin cell that has a mutation on MEK that turns it into a phospho-mimetic (it looks and acts like it has been phosphorylated at all times). You gave the cells media (the liquid the cell needs to live) but no growth factors.

Human Anatomy & Physiology (11th Edition)
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Based off this information will the cell get to the response step ? Please explain why or why not
Growth Factor (GF-signal) Activation of GF Receptor (RTK-receptor)
Signal
To cause Cell proliferation/cell division (Response)
Plasma membrane
Sos
Grb2 (Ras GEF)
(adapter)
Raf
МАРКК
Mek
МАРКК
Activation of target
genes that stimulate
Erk
МАРК
You have a skin cell that has a mutation on MEK that turns it into a phospho-mimetic (it looks and acts like it has been phosphorylated
at all times). You gave the cells media (the liquid the cell needs to live) but no growth factors.
Transcribed Image Text:Growth Factor (GF-signal) Activation of GF Receptor (RTK-receptor) Signal To cause Cell proliferation/cell division (Response) Plasma membrane Sos Grb2 (Ras GEF) (adapter) Raf МАРКК Mek МАРКК Activation of target genes that stimulate Erk МАРК You have a skin cell that has a mutation on MEK that turns it into a phospho-mimetic (it looks and acts like it has been phosphorylated at all times). You gave the cells media (the liquid the cell needs to live) but no growth factors.
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