Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Describe what cyclin dependent kinase does in the activation of MPF and how this relates to signal transduction.
Expert Solution
Step 1
Cyclin dependent kinase or CDK is catalytic and act as a protein kinase.CDKs are so named because their activities are regulated by cyclins and they catalyze the phosphorylation of specific serine and threonine residues of specific target proteins.In the fission yeast,the M-CDK activity is inhibited by protein kinase ,Wee1,which phosphorylates an inhibitory tyrosine residue at 15th position in the CDK subunit.Wee1 usually inhibits cells from initiating mitosis until their size is adequate.
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