Answered: Describe at least two Cdk regulation…

Describe at least two Cdk regulation check points during the cell cycle, Describe how that Step is regulate moluculary and what would happen if that step did not happen correctly

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter10: Cell Reproduction

Section: Chapter Questions

Problem 42CTQ: List the regulatory mechanisms that might be lost in a cell producing faulty p53.

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Figure 28.11 depicts the eukaryotic cell cycle. Many cell types â€œexitâ€� the cell cycle and donâ€™t divide for prolonged periods, a state termedG0; some, for example neurons, never divide again. a. In what stage of the cell cycle do you suppose a cell might be when it exits the cell cycle and enters G0? b. The cell cycle is controlled by checkpoints, cyclins, and CDKs. Describe how biochemical events involving cyclins and CDKs might control passage of a dividing cell through the cell cycle.
A gene that codes for a positive cell-cycle regulator is called a(n).______ kinase inhibitor tumor suppressor gene proto-oncogene oncogene.
List some reasons why a cell that has just completed cytokinesis might enter the G0 phase instead of the G1 phase.
Describe the general conditions that must be met at each of the three main cell-cycle checkpoints.
Rb is a negative regulator that blocks the cell cycle at the G1 checkpoint until the cell achieves a requisite size. What molecular mechanism does Rb employ to halt the cell cycle?
Which of the following statements about cell cycle regulators is incorrect? a. The concentrations of cyclins change throughout the cell cycle. b. Cyclins are present in all stages of the cell cycle except S. c. Cyclin-Cdk complexes phosphorylate target proteins. d. Cdks combine with cyclin to move the cycle into mitosis. e. During anaphase of mitosis, cyclin is degraded, allowing mitosis to end.
Describe how the duplicated bacterial chromosomes are distributed into new daughter cells without the direction of the mitotic spindle.
Describe the similarities and differences between the cytokinesis mechanisms found in animal cells versus those in plant cells.
Briefly describe the events that occur in each phase of interphase.
How does NF-kB induce gene expression? A small, hydrophobic ligand binds to NF-kB, activating it. Phosphorylation of the inhibitor Ik-B dissociates the complex between it and NF- kB, and allows NF-kB to enter the nucleus and stimulate transcription. NF-kB is phosphorylated and is then free to enter the nucleus and bind DNA. NF-kB is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.
If a cell developed a mutation in its MAP2K1 gene (encodes the MEK protein) that prevented MIEK from being recognized by phosphatases, how would the EGFR signaling cascade and the cell’s behavior change?
Biologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.