2. Transaription of gene X is controlled by transcription factor A (TFA). Gene X is only transcribed when factor A is phosphorylated. Data on the tissue distribution of TFA and the activities of a protein kinase and a protein phosphatase specific for TFA are presented on the table below. What tissue will gene X be expressed? Explain. Protein kinase Protein Tissue Factor A phosphatase activity activity Muscle Heart +
Q: Cystic hibros Ife-threatering disease that causes thick, stcky mucus to buid up in areas of the…
A: DNA is the genetic material in living organisms that is transcribed into mRNA. This mRNA is used for…
Q: 1. Maltose is a disaccharide of L- Explain in 2-3 sentences why you chose this answer. a. glucose…
A: meaning sugar. Hence Disaccharide is made up of two sugars. Here two monosaccharides are joined by…
Q: Why is it sometimes difficult to get needed information from patients?
A: The care in nursing can be outlined as the services a healthcare agency provides to individuals who…
Q: Adults randomly selected in the lottery were given the option to apply for Medicaid, but not did not…
A: A key idea in economic theory is the marginal efficiency of capital (MEC) curve, which depicts the…
Q: D. How many starting cell is involved in mitosis when 350 cells are produced?
A: Mitosis Mitosis is a type of cell division involving the formation of 2 daughter cells which have…
Q: Identify at least one internal process breakdown each from the front-end, middle, and back-end…
A: ORIGINAL RESPONSE: Healthcare insurance claim denial is a significant issue that affects both…
Q: Given that the first division of the zygote divides the embryo into the future right and left halves…
A: Introduction :- The zygote has the XXXX genotype. if non disjunction occur in first meiosis the…
Q: Prostaglandins are one class of the fatty acid derivatives called eicosanoids. Prostaglandins…
A: Enzymes are protein molecules that increase the rate of reaction by decreasing the activation…
Q: n an F1 cross, Y/y x Y/y, 3/4 of the plants are yellow and 1/4 of the plants are green. Determine…
A: When two dominant parents produce a 3:1 phenotypic ratio in the offspring, it indicates that both…
Q: What is the goal of this diagnosis using this scenario in a nursing care plan
A:
Q: Knowledge Activity: Inpatient Coding (Becker)
A: Activities:1. Introduction to Inpatient CodingDefine inpatient coding and its purpose: Inpatient…
Q: Can you give further explanations regarding this topic? We are about to tackle this in our next…
A: Our DNA is made up of four bases which are A= Adenine, C= Cytosine, G= Guanine, and T= Thymine. Here…
Q: QUESTION 9 mc The line of evidence used to support the concept of evolution that deals with looking…
A: Evolutionary developmental biology is considered a new norm in evolutionary biology. It arose from…
Q: If phyla Ctenophora and Coildaria, along with ther last lommon anceslar, were comblaed as group…
A: Hi, Thanks For Your Question. Answer : (I) Monophyletic
Q: If a student comes to you with signs of child abuse or neglect and you want to have visual evidence,…
A: Here we have mention the correct statement regarding a student comes with the signs of child abuse…
Q: Look at the given figure which shows the effect of light on the rate of photosynthesis. Based on the…
A: In science, photosynthesis can be explained as the physiological activity of autotrophic organisms…
Q: What is one of the issues related to compliance in the realm of healthcare coding, how can the…
A: Medical coding is the process of converting medical diagnoses, procedures and services into generic…
Q: Why it i
A: Functions like reimbursement, benchmarking, clinical and financial decision making, healthcare…
Q: Quion Some Statement about 2 DNA in which who is the not not buve about the 2 DNA structure ?…
A: DNA (deoxyribonucleic acid) is a type of nucleic acid, in which the pentose sugar is deoxyribose.…
Q: 6. (top or bottom) Species A, B, C, D, and, E are all extant species (living today, not to be…
A: Note: According to the guidelines, we are answering the first question here. Please repost the other…
Q: I am having trouble conducting a search for articles for this PICOT question. I would like to use…
A: You can improve the precision and clarity of your PICOT inquiry. I'll also provide some criticism…
Q: Styles Editing 50% of the offsprings will be hornless Hh and 50% of the offsprings will be horned hh…
A: Given information: Genotype of red raddish- RR Genotype of white raddish-WW Genotype of purple…
Q: What is the main function of the DNA? * O It can be mutated. It stores information for protein…
A: Introduction: DNA stands for 'deoxyribonucleic acid' and it is the hereditary material in humans and…
Q: Describe the level organization in the human body What are carbohydrates, lipids, and proteins, and…
A: Life processes of the human body are kept up with at a few levels of structural organization. The…
Q: 9 J A 8 K 10
A: Phylogenetic tree can be defined as the diagram which shows the relationship between evolutionary…
Q: The possession of one of two types of earlobes (hanging or attached) is sometimes used to study the…
A: Pedigree is a family tree drawn with standard genetic symbol ( genealogical table, chart or diagram)…
Q: Which of the following is NOT TRUE of the neuromuscular junction? O presynaptic calcium influx…
A: Calcium ions activate the exocytosis of the synaptic vesicle which contains neurotransmitters and it…
Q: A cell experiences a mutation where the DNA polymerase III enzyme can now add nucleotides to either…
A: A "nucleic acid" is a linear polymer of nucleotides that is a component of the cell's information…
Q: The HbS gene produces sickle-shaped RBC in man. Its normal allele is called HbA. The incidence of…
A: Sickle cell anemia Sickle cell anemia is an autosomal recessive disorder.
Q: 4. If pathogens enter your body an inflammatory response is activated. Describe what happens near…
A: Inflammation is a process by which your body's white blood cells and the things they make protect…
Q: Options are on the right. I need to match them to the statements on the left.
A: The bone tissue is of two types- Compact and spongy. Compact bone- The osteon forms the structural…
Q: QUESTION 9 Platelet-derived growth factor (PDGF) is a mitogen that activates tyrosine kinase…
A: *Platelet derived growth factor (PDGF) is activator for cells which are mesenchymal in origin and…
Q: If its possible, can you give me explanation on how to find the answers?
A: Chi-square A chi square test is a statical test to find out the similarity and different between…
Q: TCA cycle
A: TCA cycle is known as Tricarboxylic acid cycle. it is also known as Kreb's cycle. This pathway is…
Q: Which of the following is a result of agriculture? Sedentarism Nomadism Egalitarianism Foraging
A: To determine: To determine the result of agriculture from the given options
Q: Alicia is 48 year old female of 76 kilograms and height of 161.5 centimetres. Although she attempted…
A: According to our Q& A guidelines, we are supposed to answer only three sub-parts, so please…
Q: The park grounds keepers recently applied high nitrogen fertilizer to the grass surrounding the…
A: The above-give image is of Cyanobacteria. Cyanobacteria or blue-green algae are a group of bacterial…
Q: DNA Structure On the diagram: Label the 3' and 5' ends. G Circle a nucleotide Label the sugar and…
A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. If you need help with other sub…
Q: consider a patient-specific example of how lack of knowledge pertaining to pharmacology could…
A: The nurses also plays a vital role in the administration of the medication as per the doctor's…
Q: In ecological field experiments to address environmental dynamics (like annual variation in climate)…
A: Ecology The study of relationship of living organisms with their non living environment is known as…
Q: Which of the following lists the three steps of translation in their proper sequence? O 1.…
A: Translation is defined as the process of protein synthesis. It takes place in the cytoplasm.
Q: Which of the following statements about hormones is false? Hormones can affect the organization of…
A: Introduction Hormones are the chemical compounds crucial for life. Chemically they can be either…
Q: List the important ideas in the video.
A: An organism's genome is defined as all of the genetic information that is passed down from…
Q: If you grow Trp R E.coli cells in a medium containing tryptophan, which of the following stem-…
A: The tryptophan binds to the trp repressor and causes it to change shape, converting into its active…
Q: Prescriptions, biennial inventories, invoices, and Forms 222 and 41 must be readily retrievable…
A: "Records and inventory" denotes an organization's systematic documenting and tracking of many forms…
Q: A.) Assuming there is random mating, find the gene frequencies, genotypic frequencies, and the…
A: Allele frequency refers to the frequency of an allele in a population. It is computed by multiplying…
Q: Which of the following is an INCORRECT statement? (Check all that apply) At Metaphase II, a human…
A: Mitosis is one of two types of cell division in which somatic diploid cells will be divided and…
Please show complete explanation/justification/solutions clearly
![2. Transaription of gene X is controlled by transcription factor A (TFA). Gene X is only transcribed when factor A is
phosphorylated. Data on the tissue distribution of TFA and the activities of a protein kinase and a protein
phosphatase specific for TFA are presented on the table below. What tissue will gene X be expressed? Explain.
Protein
kinase
Protein
Tissue
Factor A
phosphatase
activity
activity
Muscle
Heart](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ffadfb5fc-1681-4de7-864b-c874db8ac2a3%2Fd81e5111-a698-49f2-9f43-089db973af60%2F64yl1rr_processed.jpeg&w=3840&q=75)
![](/static/compass_v2/shared-icons/check-mark.png)
Step by step
Solved in 2 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
- TNF-alpha treatment of prostate carcinoma, LNCAP cells decreases cell survival as shown in the graph below. Which of the following would you observe in these cells treated with TNF- alpha? Select all that apply TNF-a 120 100 80 - 60 40 20 0. 24 72 (hrs) Control + TNF-a 100 ng TNFA 10 ng O Activation of extrinsic pathway of apoptosis O Activation of intrinsic pathway of apoptosis Activation of executioner caspases Recruitment of adapter protein FADD to the TNF-alpha receptor LNCAP cell viability (% of control)The PYK gene codes for the expression of pyruvate kinase, which is one of the enzymestargeted for anti-cancer drug design. You have identified an RNAi that targets the mRNAof PYK gene. To study the effect of the RNAi towards pyruvate kinase, the respected RNAiis expressed in Saccharomyces cerevisiae. The level of pyruvate kinase can be detectedwith a fluorescent antibody.(a). Predict the result that you will obtain in recombinant S. cerevisiae that expresses therespected RNAi.(b). Compare the result in Q3a(i) with the wild-type S. cerevisiae.1 of 16 Data from an experiment is shown in the figure below. In the experiment, murine cells were treated with a specific a ligand that activates receptor R. In some cases, the cells were exposed to one of two drugs (X or Y) as well as the ligand or were left untreated (UT). After 30 minutes of treatment, the cells were lysed with a detergent-based buffer to release the soluble membrane, cyosolic and nuclear proteins. Samples from each cell extract were run (in duplicate) by SDS-PAGE (SDS-polyacrylamide gel electrophoresis) in order to separate the proteins by molecular mass (size). The separated proteins were then transferred to a nitrocellulose membrane which was then probed with different antibodies in a western blotting procedure to detect specific phosphorylated proteins or total proteins. If present in the cell extract, these proteins appear as a dark band in the relevant western blot image within the figure. Drug X Drug Y UT Ligand Ligand Ligand Western blotting antibodies…
- 5) Briefly explain why the formation of a tumour can pose a risk to a person's homeostasis. 6) The functioning of the "Ras/MAPK" signal transduction pathway is absolutely essential in order for cells to grow, divide, and migrate. One important protein that is part of this pathway is BRAF. This protein is a kind of enzyme called a "kinase" – an enzyme that transfers a phosphate group onto another protein. In some melanomas, a mutated form of BRAF called BRAF Val600AGlu drives the progression of the cancer. The drug "vemurafenib" slows the progression of the cancer by slowing the production of the mutant BRAF protein. (National Cancer Institute. 2019. Types of Cancer Treatment. Retrieved from: https://www.cancer.gov/about-cancer/treatment/types/ Is this an example of a traditional cancer therapy or a targeted therapy? Briefly explain your reasoning in the space provided, using information provided in the text to support your answer. Type of therapy (traditional or targeted)?: Brief…BCL2 binds to and inactivates BAX and other pro-apoptotic proteins, thereby inhibiting apoptosis. Venetoclax has been approved for marketing in patients with chronic lymphocytic leukemia (CLL) Venetoclax is a highly selective BCL2 inhibitor that disrupts the interaction of this protein with BH3 domain proteins thereby permitting apoptosis. Proapoptotic Proapoptotic proteins protein binds to BCL2 BCL2 Venetoclax Venetoclax displaces proapoptotic proteins BCL2 Venetoclax Proapoptotic proteins No venetoclax binding BCL2 Glys01Val mutation Which of the following can you conclude from this information? Select all that apply Bcl2- mutations that prevent Ventoclax binding promote cell survival Venetoclax binding to Bcl2 promotes cell survival . Venetoclax binding to Bcl2 promotes cell death Proapoptotic protein binding to Bcl2 promotes cell survivalThe progressive loss of cardiac myocytes due to cell death has been associated with cardiac dysfunction and heart failure. Which of the following would lead to a significant loss of cardiac myocytes? Select all that apply Treatment of rapamycin which results in inhibition of mTOR activity Prolonged or severe ER stress with increased accumulation of unfolded proteins Activation of AMPK and phosphorylation of the TSC1 complex mTOR activation and phosphorylation of Ulk1
- 1.Describe in detail the signal transduction pathway that leads to activation of either PKA, Kinase or PC. 2. Describe in detail the signal transduction pathway that leads to activation of MAPKinase or Akt/PKB. 3.Describe the similarities and differences in the structures of GPCRs specific for various ligands including the extracellular , transmembrane , and intracellular domains.TGF-B Receptor I (RI) phosphorylation of Smad2/3 does all of the following EXCEPT: activate Smad2/3 binding to the Co-Smad Smad4 dissociate intramolecular binding of Smad2/3 MH1 and MH2 domains. RI phosphorylation of Smad2/3 does all of these things. release Smad2/3 from the nucleus into the cytoplasm unmask the Smad2/3 nuclear localization signal (NLS).TNF-alpha treatment of prostate carcinoma, LNCAP cells decreases cell survival as shown in the graph below. Which of the following would you observe in these cells treated with TNF- alpha? Select all that apply TNF-a 120 100 80 - 60- 40- 20 - 24 72 (hrs) + Control - TNF-a 10ng + TNF-a 100 ng O Activation of extrinsic pathway of apoptosis O Activation of intrinsic pathway of apoptosis Activation of executioner caspases Recruitment of adapter protein FADD to the TNF-alpha receptor LNCAP cell viability (% of control)
- Plasma PDGF levels can be a diagnostic marker for severity and progression of breast cancer. The assay data below shows the plasma levels of PDGF in normal individuals, Stage II and Stage IV (More severe). You are treating a patient with breast cancer and assay indicates that their plasma PDGF level 6 fmoles/ 100 uL.Based on this info, in which stages has this patient's cancer progressed? Explain what process this patient's tumor has likely undergone and which cell types you would expect to now be associated with this tumor.which of hthe following would result in a persisting proliferation response to growth factor receptor activation after the ligand is no longer binding to its rceptor kinase? 1. Both a mutation that blocks the GTPas activity of Ras and a mutation that blocks the exchange of GDP with GTP would cause the response to persist. 2. a mutation that blocks the GTPas activity of Ras 3. neither a mutation that blocks the GTPas activity of Ras nor a mutation that blocks the exchange of GDP with GTP would cause the response to persist 4. a mutatiaon that blocks the exchange of GDP with GTPa.What would happen if IKKbeta did not phosphorylate IkappaB? b.Why is it so hard to make cytokine therapies? c.Why would you use the MyD88 independent pathway versus the MyD88 dependent pathway?
![Biology 2e](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
![Biochemistry](https://www.bartleby.com/isbn_cover_images/9781305577206/9781305577206_smallCoverImage.gif)
![Biology 2e](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
![Biochemistry](https://www.bartleby.com/isbn_cover_images/9781305577206/9781305577206_smallCoverImage.gif)