Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 10, Problem 8TYK
Which of the following statements about cell cycle regulators is incorrect?
a. The concentrations of cyclins change throughout the cell cycle.
b. Cyclins are present in all stages of the cell cycle except S.
c. Cyclin-Cdk complexes phosphorylate target proteins.
d. Cdks combine with cyclin to move the cycle into mitosis.
e. During anaphase of mitosis, cyclin is degraded, allowing mitosis to end.
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Which of the following statements about the cell cycle is TRUE?
a. The protein APC blocks cells from entering anaphase
b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins
c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation
d. Cyclin proteins must be degraded before Cdk proteins can be activated
Passage of cells from G1 through R to S depends on the interaction of various signal molecules, proteins and enzymes which regulate the cell cycle. Imagine I have just induced a mutation in a cell line which prevents the breakdown of the cyclin molecule we discussed. Which of the following events do you predict will happen?
circle all that apply
Select one or more:
a. Uncontrolled cell replication may result
b. Retinoblastoma protein will be continuously active
c. The cells will be stuck in G1 phase
d. The cells will begin to replicate their DNA
e. Cyclin dependent kinase (Cdk) will be continuously active
Cyclins and cyclin-dependent kinases regulate progression through the cell cycle. Which of the following determines progression beyond the
restriction point in G1?
Select one:
a. The presence of cyclin and Cdk.
O b. The presence of cyclin.
c. Phosphorylation of RB by Cdk.
d. The presence of external signals from growth factors.
e. The absence of cyclin.
Chapter 10 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 10.1 - What are the three interrelated systems that...Ch. 10.1 - Prob. 2SBCh. 10.1 - Prob. 3SBCh. 10.1 - Prob. 4SBCh. 10.2 - Compare the chromosome content of daughter cells...Ch. 10.2 - Prob. 2SBCh. 10.2 - Prob. 3SBCh. 10.3 - How does spindle formation differ in animals and...Ch. 10.3 - Prob. 2SBCh. 10.4 - Prob. 1SB
Ch. 10.4 - Prob. 2SBCh. 10.4 - What is an oncogene? How might an oncogene affect...Ch. 10.4 - Prob. 4SBCh. 10.5 - Prob. 1SBCh. 10.5 - Prob. 2SBCh. 10 - During the cell cycle, the DNA mass of a cell:...Ch. 10 - A tumor suppressor protein, p21, inhibits Cdk1....Ch. 10 - A major difference between hereditary information...Ch. 10 - The major microtubule organizing center of the...Ch. 10 - Prob. 5TYKCh. 10 - Which of the following statements about mitosis is...Ch. 10 - Prob. 7TYKCh. 10 - Which of the following statements about cell cycle...Ch. 10 - Which of the following is not a characteristic of...Ch. 10 - Which of the following does not accurately...Ch. 10 - In bacteria: a. several chromosomes undergo...Ch. 10 - Prob. 12TYKCh. 10 - Discuss Concepts A cell has 38 chromosomes. After...Ch. 10 - Prob. 14TYKCh. 10 - Prob. 15TYKCh. 10 - Apply Evolutionary Thinking The genes and proteins...Ch. 10 - Biologists have long been interested in the...Ch. 10 - Prob. 2ITD
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- Researchers studying cell cycle regulation in budding yeast have observed that a mutation in the CDC15 gene causes cell cycle arrest in telophase when the yeast cells are incubated at an elevated temperature. Which of the following statements best predicts the effect of the cell cycle arrest on proliferating yeast cells? A. Restate the question and record the right answer. B. Why is this the correct answer?arrow_forwardBPA is a chemical compound that has historically been used in the manufacture of plastic products. However, cells often mistake BPA molecules for hormones that accelerate the cell cycle. Because of this, BPA is associated with an increased risk of certain cancers.a. How might BPA interact with the cell cycle and its checkpoints?b. Why do you think that very small concentrations of BPA might have a large effect on a cell?arrow_forwardWhich of the following statements is FALSE? A. Centrosomes are anchor points for microtubules and are essential to form the mitotic spindle. B. In the eukaryotic cell cycle the cell spends much more time in the interphase than in the mitotic phase. C. In telophase two nuclear envelopes are fully formed and the cell splits in two via cytokinesis. D. The contraction of the kinetochore microtubules leads to the separation of the sister chromatids during anaphase. E. In the prophase chromatin condenses into X-shaped chromosomes.arrow_forward
- What celluar events/processes are associated with G1,S,G2,and M phases of the cell cycle? With the phases of mitosis? Some example: A. DNA replication B. Beginning of mitosis C. Normal cell growth and function D. Breaksdown of nuclear membrane E.Separation of sister chromatids F.Alignment of chromosomes on the equator of the cell H.Triggering the compaction and condensation of chromosomes I. Attachment of microtubles to kinetochoresarrow_forwardBPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: How might BPA interact with the cell cycle and its checkpoints?arrow_forwardLooking at the the time intervals in the figure given, compare the time spent in mitosis with the time spent in gap1 in human liver cells. A. less time is spent in G1 than in M B. a little more time is spent in G1 than in M C. The cell spends 10 hours less in G1 than it does in M D. The cell spends 10 hours more in G1 than it does in Marrow_forward
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