Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 10, Problem 7TYK
Summary Introduction
Introduction:
Cell division is a process where the cell divides to form two daughter cells. It enables the growth reproduction and repair of cells and tissues. The cell cycle includes the G1, S, G2, and M stages. The M phase is the main mitotic phase where nuclear division takes place.
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Which of the following is true of normal adult cells but NOT cancer cells?
A. Cell death after a finite number of cell divisions
B. Contact with other cells increases likelihood of division
C. Large amount of telomerase present D. Do not care about cell density while culture
The metaphase to anaphase transition involves
a. new force being generated to pull the chromatids apart.
b. an increase in force on sister chromatids to pull them apart.
c. completing DNA replication of centromeres allowing chromosomes to be pulled apart.
d. loss of cohesion between sister chromatids.
The following diagram indicates how the cell cycle progresses in typical human cells:
INTERPHASE
G₁
MITOTIC
(M) PHASE
Mitosis
Cytokinesis
DRUG
S
(DNA synthesis)
G2
Suppose that you are investigating potential drugs that might be used to stop the out of control growth
of tumor cells. The following table lists several experimental drugs along with some information about
their effect on cells. Predict which stage of the cell cycle might be inhibited by each of the drugs (A
through E).
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Chapter 10 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 10.1 - What are the three interrelated systems that...Ch. 10.1 - Prob. 2SBCh. 10.1 - Prob. 3SBCh. 10.1 - Prob. 4SBCh. 10.2 - Compare the chromosome content of daughter cells...Ch. 10.2 - Prob. 2SBCh. 10.2 - Prob. 3SBCh. 10.3 - How does spindle formation differ in animals and...Ch. 10.3 - Prob. 2SBCh. 10.4 - Prob. 1SB
Ch. 10.4 - Prob. 2SBCh. 10.4 - What is an oncogene? How might an oncogene affect...Ch. 10.4 - Prob. 4SBCh. 10.5 - Prob. 1SBCh. 10.5 - Prob. 2SBCh. 10 - During the cell cycle, the DNA mass of a cell:...Ch. 10 - A tumor suppressor protein, p21, inhibits Cdk1....Ch. 10 - A major difference between hereditary information...Ch. 10 - The major microtubule organizing center of the...Ch. 10 - Prob. 5TYKCh. 10 - Which of the following statements about mitosis is...Ch. 10 - Prob. 7TYKCh. 10 - Which of the following statements about cell cycle...Ch. 10 - Which of the following is not a characteristic of...Ch. 10 - Which of the following does not accurately...Ch. 10 - In bacteria: a. several chromosomes undergo...Ch. 10 - Prob. 12TYKCh. 10 - Discuss Concepts A cell has 38 chromosomes. After...Ch. 10 - Prob. 14TYKCh. 10 - Prob. 15TYKCh. 10 - Apply Evolutionary Thinking The genes and proteins...Ch. 10 - Biologists have long been interested in the...Ch. 10 - Prob. 2ITD
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- One difference between cancer cells and normal cells is that cancer cells a. are always in the M phase b. are arrested at the S phase of the cell cycle c. are unable to synthesize DNA d. continue to divide even when they are tightly packed togetherarrow_forwardWhich of the following statements about mitosis is incorrect? a. Microtubules from the spindle poles attach to the kinetochores on the chromosomes. b. In anaphase, the spindle separates sister chromatids and pulls them apart. c. In metaphase, spindle microtubules align the chromosomes at the spindle midpoint. d. Cytokinesis describes the movement of chromosomes. e. Both the animal cell furrow and the plant cell plate form at their former spindle midpoint.arrow_forwardWhich of the following statements about the cell cycle is TRUE? a. The protein APC blocks cells from entering anaphase b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation d. Cyclin proteins must be degraded before Cdk proteins can be activatedarrow_forward
- The drug taxol is extracted from the bark of yew trees. It binds tightly to microtubules and stabilizes them. When added to cells, it causes much of the free tubulin to assemble into microtubules. Taxol can be used as an anticancer drug. At the molecular level, what does the drug prevent? At the cellular level, what part of cell division does it prevent? Be specific.arrow_forwardWhich of the following statements is FALSE? A. Centrosomes are anchor points for microtubules and are essential to form the mitotic spindle. B. In the eukaryotic cell cycle the cell spends much more time in the interphase than in the mitotic phase. C. In telophase two nuclear envelopes are fully formed and the cell splits in two via cytokinesis. D. The contraction of the kinetochore microtubules leads to the separation of the sister chromatids during anaphase. E. In the prophase chromatin condenses into X-shaped chromosomes.arrow_forwardProgression through the cell cycle is dependent on both extra- and intracellular conditions. Consider the following conditions. Indicate which checkpoint (s) responds to that condition.a. The cell is large enough to divide.b. The DNA is completely copied during S phase.c. The cell is receiving positive cues from neighbors.d. The DNA is damaged.e. The cell has enough energy reserves to divide.f. Are all the sister chromatids correctly attached to spindle microtubules?arrow_forward
- Passage of cells from G1 through R to S depends on the interaction of various signal molecules, proteins and enzymes which regulate the cell cycle. Imagine I have just induced a mutation in a cell line which prevents the breakdown of the cyclin molecule we discussed. Which of the following events do you predict will happen? circle all that apply Select one or more: a. Uncontrolled cell replication may result b. Retinoblastoma protein will be continuously active c. The cells will be stuck in G1 phase d. The cells will begin to replicate their DNA e. Cyclin dependent kinase (Cdk) will be continuously activearrow_forwardWhich of the following statements is true regarding cell cycle regulators? a. Cyclins determine which proteins each Cdks will act on. b. Cdks check the DNA for damage and repairs it. c. Cyclin binding to Cdks will result to Cdk inactivation. d. Cyclin levels remain constant through the cell cycle.arrow_forwardThe growth period of the cycle is considered as the interphase in which one of the prominent parts is that time wherein the cells make a copy of the genetic material in the form of nuclear DNA. This is particularly termed as a. synthesis b. Gap 1 c. Gap 2 d. Interphasearrow_forward
- Match the following terms with the correct description Go phase A. During this phase, the cell divides into two identical cells. G, phase B. During this phase, the cell grows In size and synthesizes MRNA Gz phase C. This phase directly precedes mitosis. s phase D. This phase can be percelved as a moment in time in which the cell is nelther dividing nor preparing to divide. M phase E. DNA Is replicated during this phase.arrow_forwardWhich of the following is MOST likely true of aggressively dividing cancer cells (select one)? A. They do not express telomerase B. They do not express hTERT C. They are in a state of cell crisis D. Their telomeres are stabilized (not shortening with each cellular division) E. None of Abovearrow_forwardWhy is a rapidly growing tissue, such as the root tip of a plant, a good model for studying the effects of a drug on cell division?arrow_forward
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