Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 10.4, Problem 3SB
What is an oncogene? How might an oncogene affect the cell cycle?
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Which of the following is an example of a proto-oncogene?
1) cell cycle inhibitor
2) tumor suppressor
3) oncogene
4) repair enzyme
5) growth factor receptor
Which of the following is true with respect to cyclins and CDKs?
A) CDKs promote progression of the cell cycle, cyclins function to inhibit progression of the cell cycle
B) CDKs are the checkpoints in the cell cycle, and when bound to cyclins, they stop progression of the cell cycle
C) CDKs will only work to promote progression of the cell cycle when complexed with their designated cyclins
D) CDKs are rarely expressed during a cell's cycle, unless cyclins are present to act as transcription factors
.
What is the key difference between anaphase I and anaphase II?
Chapter 10 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 10.1 - What are the three interrelated systems that...Ch. 10.1 - Prob. 2SBCh. 10.1 - Prob. 3SBCh. 10.1 - Prob. 4SBCh. 10.2 - Compare the chromosome content of daughter cells...Ch. 10.2 - Prob. 2SBCh. 10.2 - Prob. 3SBCh. 10.3 - How does spindle formation differ in animals and...Ch. 10.3 - Prob. 2SBCh. 10.4 - Prob. 1SB
Ch. 10.4 - Prob. 2SBCh. 10.4 - What is an oncogene? How might an oncogene affect...Ch. 10.4 - Prob. 4SBCh. 10.5 - Prob. 1SBCh. 10.5 - Prob. 2SBCh. 10 - During the cell cycle, the DNA mass of a cell:...Ch. 10 - A tumor suppressor protein, p21, inhibits Cdk1....Ch. 10 - A major difference between hereditary information...Ch. 10 - The major microtubule organizing center of the...Ch. 10 - Prob. 5TYKCh. 10 - Which of the following statements about mitosis is...Ch. 10 - Prob. 7TYKCh. 10 - Which of the following statements about cell cycle...Ch. 10 - Which of the following is not a characteristic of...Ch. 10 - Which of the following does not accurately...Ch. 10 - In bacteria: a. several chromosomes undergo...Ch. 10 - Prob. 12TYKCh. 10 - Discuss Concepts A cell has 38 chromosomes. After...Ch. 10 - Prob. 14TYKCh. 10 - Prob. 15TYKCh. 10 - Apply Evolutionary Thinking The genes and proteins...Ch. 10 - Biologists have long been interested in the...Ch. 10 - Prob. 2ITD
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- What kind of daughter cells will result if the "Normal cell" above goes through mitosis? A) two normal cells B) two cancer cells C) two specialized cells D) one cancer cell and one normal cellarrow_forwardDuring cell cycle there are checkpoints. They best way to define a checkpoint is? a) a location within the cell where proteins are inspected for mutations b) G1, S, G2, prophase metaphase anaphase or telophase c) specific stages where further progress of the cell cycle can be halted d) any step where the cell cycle is blocked by a mutated proteinarrow_forwardWhat are the roles of cellular proto-oncogenes, and how are these roles consistent with their implication in oncogenesis?arrow_forward
- The interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin. a) What is chromatin? b) How can the chromatin structure change?arrow_forwardWhat protein does the P53 code for and why is it important?arrow_forwardDefine oncogenearrow_forward
- What are the three protein families that regulate the cell cycle? give an example for each:arrow_forwardWhich of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin gene to be expressed at all times during the cell cycle B) a mutation that causes an oncogene to be turned off so that no protein is made C) a mutation that causes a Cdk gene to be turned off so that no protein is made D) a mutation that causes a tumor suppressor gene to be over-expressedarrow_forwardHow does the dysregulation of cell cycle checkpoints contribute to the development of cancer?arrow_forward
- How do cyclins and CDKs differ? How do they interact in controlling the cell cycle?arrow_forwardA cell inherits a mutation in a gene that results in a transcription factor, called NF-kB, constantly being in its active conformation. When active, NF-kB stimulates the expression of cyclins that promote progression of the cell cycle, regardless of other conditions. As a result of this mutation, how would this cell's phenotype be affected by this mutation? A) This cell would have a cancer phenotype B) This cell would grow larger in size, but would never divide C) This cell would likely undergo apoptosis D) This cell would not duplicate its chromosomes .arrow_forwardHow do BRCA1 and BRCA2 function in regard to cell proliferation (are they proto-oncogenes, oncogenes, or tumor suppressor genes)?arrow_forward
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