The figure below shows 6 genes that are differentially expressed based on theirspecific enhancers. The different activators (A-F) are proteins that can bind to theappropriate control element in the enhancers of these genes. Use the diagram toanswer the following question: What gene(s) would be transcribed if you A, C,E and F enhancers had activators bound to them? No need to explain youranswer – just provide the gene(s).ABCDPromoterBrain specific geneABCF PromoterLiver specific geneCPromoterHeart specific geneACDPromoterSkin specific geneABDPromoterGut specific geneEF PromoterNose specific gene

Name: The figure below shows 6 genes that are differentially expressed base
Uploaded: 2024-03-20T06:42:41.000Z
Channel: Bartleby
Description: The figure below shows 6 genes that are differentially expressed based on theirspecific enhancers. The different activators (A-F) are proteins that can bind to theappropriate control element in the enhancers of these genes. Use the diagram toanswer

Enhancers are the regulatory sequences in the DNA located farther away from the transcription start site that helps in enhancing or increasing the transcription of the genes involved. These are also known as positive transcriptional control elements. They help in increasing the basal transcription level of the genes involved initiated through the core promoter elements. Activator is the protein that binds to these enhancer elements in the DNA and thus helps in gene transcription enhancement. These activators have generally two domains - One is the activation domain and the other is DNA binding domain. Based on the given figure, it can be seen that if - 1) An activator gets bound to enhancers A, B, C, and D, then the brain-specific genes are activated. 2) An activator gets bound to enhancers A, B, C, and F, then the liver-specific genes are activated. 3) An activator gets bound to enhancers A, C, and E, then the heart-specific genes are activated. 4) An activator gets bound to enhancers A, C, and D, then the skin-specific genes are activated. 5) An activator gets bound to enhancers A, B, and D, then the Gut-specific genes are activated. 6) An activator gets bound to enhancers E, and F, then the nose-specific genes are activated. Now if the activators are bound to A, C, E, and F enhancers then the genes which are activated are heart and nose specific genes. So the correct answer is heart and nose specific genes are activated.