NCAM is a gene that is normally only transcribed in neurons. How could you induce (force) expression of NCAM in muscle cells? Group of answer choices A. In the muscle cell, express the tissue-specific transcription factor from neurons that binds the NCAM enhancer (i.e., put the neuron TS TF into the muscle cell) B. In the muscle cell, mutate the NCAM enhancer sequence so that another tissue-specific transcription factor already present in the muscle cell can bind to it C. Add the promoter region of the NCAM gene to the muscle cell D. All of the above E. Only A and B are correct

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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NCAM is a gene that is normally only transcribed in neurons. How could you induce (force) expression of NCAM in muscle cells?
Group of answer choices

A. In the muscle cell, express the tissue-specific transcription factor from neurons that binds the NCAM enhancer (i.e., put the neuron TS TF into the muscle cell)

B. In the muscle cell, mutate the NCAM enhancer sequence so that another tissue-specific transcription factor already present in the muscle cell can bind to it

C. Add the promoter region of the NCAM gene to the muscle cell

D. All of the above

E. Only A and B are correct

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