Mutations in bacterial promoters may increase or decrease the rate of gene transcription. Promoter mutations that increase the transcription rate are termed up-promoter mutations, and those that decrease the transcription rate are termed down-promoter mutations. If the promoter for the lac operon is TATGTT, would the following be uppromoters or downpromoters? A. TATGTT to TATATT B. TATGTT to TTTGTT C. TATGTT to TATGAT
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Mutations in bacterial promoters may increase or decrease the rate of gene transcription. Promoter mutations that increase the transcription rate are termed up-promoter mutations, and those that decrease the transcription rate are termed down-promoter mutations. If the promoter for the lac operon is TATGTT, would the following be uppromoters or downpromoters?
A. TATGTT to TATATT
B. TATGTT to TTTGTT
C. TATGTT to TATGAT
The -10 site sequence in bacterial promoters is essential for RNA polymerase binding and transcription initiation. Different effects on the rates of gene transcription can result from mutations in this region.
The consensus sequences that are located either partially downstream or upstream of the gene are known as promoters. Promoters increase the specific gene's rate of expression.
Any gene can have a mutation that results in increased or decreased expression.
Any mutation in a promoter that results in increased control of gene expression is referred to as an up-promoter; if it results in decreased gene expression, it is referred to as a down-promoter
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