Which of the following statements about the enzyme adenylate cyclase (AC) is FALSE?AC is activated by the presence of lactoseAC helps E. coli optimize metabolism by favoring consumption of easy-to-digest sugars when they are available.AC links the alpha phosphate on the 3' carbon of ATP to the 5' carbon as well, forming cyclic AMPAC is inhibited by the presence of glucose IIVY is a LysR regulator, and it helps control transcription of a neighboring gene, ilvC. IlvY can eitherbend the DNA and block RNAP's access to ilvC's -35 promoter site, or it can allow access to the ilvC -35site, thereby promoting ilvC transcription. What determines whether llvY is repressing or activatingtranscription from the ilvC promoter?The presence of the co-inducer acetolactate - acetolactate binds to llvY and changes llvY's shape such that itdoesn't block the -35 of the ilvC promoter.IlvY represses ilvC transcription when the IlvC protein is bound to llvY, and it activates ilvC transcription whenthe lvC protein is not present to bind to llvY.The presence of the co-inducer valine - when valine is present, it binds llvY and causes llvY to represstranscription from the ilvC promoter.The presence of the co-inducer acetolactate - acetolactate induces negative supercoiling at the ilvC promoter,which represses ilvC transcription.

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O AC is activated by the presence of lactose AC helps E. coli optimize metabolism by favoring consumption of easy-to-digest sugars when they are availabi AC links the alpha phosphate on the 3' carbon of ATP to the 5' carbon as well, forming cyclic AMP AC is inhibited by the presence of glucose

O AC is activated by the presence of lactose AC helps E. coli optimize metabolism by favoring consumption of easy-to-digest sugars when they are availabi AC links the alpha phosphate on the 3' carbon of ATP to the 5' carbon as well, forming cyclic AMP AC is inhibited by the presence of glucose

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Many years later, in 1989, Wild, et al. revisited the idea of allosteric control of ATCase by CTP. They noted that CTP did indeed inhibit ATCase, but that the inhibition was always incomplete, even at high concentrations of CTP. They hypothesized that perhaps CTP did not act alone, but in combination with some other nucleotide. They tested the activity of ATCase in the presence of several nucleotide combinations. The results are shown in Table 3. a. What combination gives the most effective inhibition? b. What is the physiological significance of this combination? c. Revise Figure 1 to include this new information. d. Redraw Figure 2 to include this new information. How does the combination compare with the values for the nucleotides alone? Table 3: Relative specific activities for combinations of nucleotide effectors. A value greater than one indicates stimulation, a value less than one indicates inhibition. Nucleotide Effector ATP CTP GTP UTP ATP/CTP ATP/GTP ATP/UTP CTP/GTP CTP/UTP…
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