Transcriptional regulation relies on chromatin modifications that affect the physical state of chromatin and the accessibility of genomic DNA to RNA polymerase. This is commonly referred to as epigenetic regulation of gene expression, and it is highly dynamic. Epigenetic modifications vary from cell to cell and vary over time and in response to different environmental conditions within the same cell. Fill in the table below based on your knowledge of the impact of different epigenetic modifications on chromatin structure and transcription.   Chromatin/DNA Modification Protei

Q: complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with…

A: PPE stands for a promoter-proximal element which is an additional promoter that contains AT-rich…

Q: You are studying how gene transcription gets started in eukaryotes. Which of the following…

A: Transcription factors are protein molecules which bind to specific DNA sequences to regulate gene…

Q: Consider the Rho-dependent terminator sequence 5’CCCAGCCCGCCUAAUGAGCGGCCUUUUUUUU-3’. What affect…

A: The mutation is the change in the nucleotide sequence of the DNA. The point mutation is the mutation…

Q: Typically, increased acetylation and decreased methylation of histone N-terminal tails in…

A: Histone acetylation and deacetylation are the processes by which the lysine deposits inside the…

Q: Glenn Croston and his colleagues studied the relation between chromatin structure and transcription…

A: Glenn Croston with his colleagues measured the level of invitro transcription of the gene in a…

Q: What has happened to the chromatin in the diagram? What regulatory proteins binds to what part of…

A: DNA is a double helical structure, which is wrapped around histones.  histones are proteins found in…

Q: Select whether each of the components are associated with eukaryotic or prokaryotic transcription.…

A: The expression of the genetic material occurs generally through the production of proteins. This…

Q: onsider Figure 3, which shows some features of a eukaryotic gene. A, B, C are exons while 1, 2 are…

A: INTRODUCTION When an RNA transcript is first made during a eukaryotic cell, it's considered a…

Q: Match the type of chromatin modification with the most likely effect on gene expression near the…

A: DNA and histone proteins, which are essential elements of the chromatin structure, are chemically…

Q: Describe the molecular steps by which polycomb group complexescause epigenetic gene silencing.

A: The PcG protein complex (Polycomb group) is one of the two protein complexes involved in the…

Q: Which of the following is NOT a property of general tra ripion O Each eukaryotic gene utilizes a…

A: Transcription factors are proteins that play a crucial role in regulating gene expression. They bind…

Q: ex determination in Drosophila is controlled by a cascade of alternative splicing events.…

A: Sxl is an RNA binding protein that participates in alternative splicing and translation.

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: stream of their coding sequence. The interaction of these enhancers with specific pression. Gene A…

A: Transcription elements Are defined as the type of proteins that have the ability to do modification…

Q: If histones are acetylated on a lysine amino acid (an epigenomic mark), are genes in this region…

A: Epigenetics is the branch of genetics that deals with changes in gene expression (no change in the…

Q: Base on your knowledge of DNA, chromosomes and epigenetics and upon examining the picture below,…

A: Epigenetic modification is the changes in chromatin structure which can result in repression or…

Q: Describe the mechanisms in which DNA is used to generate protein.  Reflect on the key points in the…

A: Deoxyribonucleic acid is a molecule composed of two polynucleotide chains that coil around each…

Q: What does the statement above mean

A:

Q: Briefly explain how different modifications of histone protein affects the epigenetics of a gene

A: Epigenetics is the study of the gene in which DNA sequence does not change. The epigenetic change…

Q: c) You use chromatin immunoprecipitation to measure the location and amount of transcription factors…

A: Transcription factors are protein molecules which bind to specific DNA sequences to regulate gene…

Q: Regulation of gene expression in eukaryotes can occur:

A: Transcription is the formation of mRNA from DNA.It occurs in nucleus. The translation is the…

Q: Which of the following are ways in which transcriptional repressors can function in eukaryotes?…

A: Enhancers are DNA regulatory elements that can enhance or increase the transcription of genes.…

Q: You wish to determine which genes are aberrantly expressed in a certain type of cancer. How would…

A: Cancer is a disease of uncontrolled gene expression. It is a proliferative disease as it can induce…

Q: The first product of genome expression is transcriptome but what happens if the RNA of the genes are…

A: Transcriptome is the collection of the all the RNAs both the coding and non-coding type present in a…

Q: Describe two different ways that histone modifications may alter chromatin structure.

A: Chromosomes appear at the time of cell division in the form of thread like structures inside the…

Q: A disease is caused by having no functional protein produced from the kip gene. An individual has…

A: Mutations are alterations in the DNA sequence of an organism. Small changes, such as adding or…

Q: Often, the physical characteristics of genetically identical twins become increasingly different as…

A: Please follow step 2 for detailed explanation.

Q: If a mutation occurred in a control element sequence associated with a particular gene, which of the…

A: Transcription is found in the nucleus. It makes RNA from template strand of DNA.

Q: Three similar proteins are expressed in human tissues: HHT1 is expressed in the liver,  HHT2 is…

A: Introduction Proteins are huge biomolecules and macromolecules that are made up of one or more long…

Q: A partial DNA sequence, a partial MRNA transcript, and part of the CFTR polypeptide in a cystic…

A: Cystic fibrosis is a disesase that damage the cell producing mucus, sweat and other juices.  in…