Alanine racemase catalyzes the reaction of L-alanine to D-alanine. The enzyme uses the coenzyme pyridoxal phosphate (PLP), which acts as an electrophile and an electron sink. Given the structures of L-alanine and pyridoxal phosphate, modify the structures to show the key intermediate containing a chiral center. Click the - in the lower right corner to shrink the structures and view completely. Modify the structures to show the key intermediate containing a chiral center. Select Groups More Draw Templates CH N ° P Erase G 47 ° ° H₂N H H Lys Enz QQQ Macmillan Learning Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This process activates mevalonate and converts it to isopentenyl pyrophosphate. Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms to denote which carbon atoms are labeled and which are not labeled. H₂C COA 14C-labeled acetyl-CoA HHH [c] H H OH 014C - OH H HH H Mevalonate CH3 H H 14C H Η H H Incorrect Answer of o -P-O-P-0- Isopentenyl pyrophosphate с Answer Bank 14C
Alanine racemase catalyzes the reaction of L-alanine to D-alanine. The enzyme uses the coenzyme pyridoxal phosphate (PLP), which acts as an electrophile and an electron sink. Given the structures of L-alanine and pyridoxal phosphate, modify the structures to show the key intermediate containing a chiral center. Click the - in the lower right corner to shrink the structures and view completely. Modify the structures to show the key intermediate containing a chiral center. Select Groups More Draw Templates CH N ° P Erase G 47 ° ° H₂N H H Lys Enz QQQ Macmillan Learning Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This process activates mevalonate and converts it to isopentenyl pyrophosphate. Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms to denote which carbon atoms are labeled and which are not labeled. H₂C COA 14C-labeled acetyl-CoA HHH [c] H H OH 014C - OH H HH H Mevalonate CH3 H H 14C H Η H H Incorrect Answer of o -P-O-P-0- Isopentenyl pyrophosphate с Answer Bank 14C
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter24: Lipid Biosynthesis
Section: Chapter Questions
Problem 2P: Tracing Carbon Atom Incorporation in Fatty Acids (Integrates with Chapters 18 and 19.) Use the...
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Transcribed Image Text:Alanine racemase catalyzes the reaction of L-alanine to D-alanine. The enzyme uses the coenzyme pyridoxal phosphate (PLP),
which acts as an electrophile and an electron sink. Given the structures of L-alanine and pyridoxal phosphate, modify the
structures to show the key intermediate containing a chiral center.
Click the - in the lower right corner to shrink the structures and view completely. Modify the structures to show the
key intermediate containing a chiral center.
Select
Groups
More
Draw
Templates
CH
N ° P
Erase
G
47
°
°
H₂N
H
H
Lys
Enz
QQQ
![Macmillan Learning
Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This
process activates mevalonate and converts it to isopentenyl pyrophosphate.
Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled
from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms
to denote which carbon atoms are labeled and which are not labeled.
H₂C
COA
14C-labeled acetyl-CoA
HHH
[c]
H
H
OH
014C
- OH
H
HH
H
Mevalonate
CH3
H H
14C
H
Η
H
H
Incorrect Answer
of o
-P-O-P-0-
Isopentenyl pyrophosphate
с
Answer Bank
14C](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F49c92b46-46f3-4d8d-a961-009feaf8829c%2Febd9cf44-17b8-4abc-b38a-6be2679a00a9%2Feoyx71_processed.png&w=3840&q=75)
Transcribed Image Text:Macmillan Learning
Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This
process activates mevalonate and converts it to isopentenyl pyrophosphate.
Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled
from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms
to denote which carbon atoms are labeled and which are not labeled.
H₂C
COA
14C-labeled acetyl-CoA
HHH
[c]
H
H
OH
014C
- OH
H
HH
H
Mevalonate
CH3
H H
14C
H
Η
H
H
Incorrect Answer
of o
-P-O-P-0-
Isopentenyl pyrophosphate
с
Answer Bank
14C
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