In the lab, metabolic poisons can be used to study ATP synthesis and oxygen consumption. Many of these poisons have - or have had - other uses, from diet aids to animal poisons to antibiotics. Poison oligomycin cyanide trifluorocarbonylcyanide phenylhydrazone (FCCP) rotenone bongkrekic acid Action binds to Fo and blocks the proton channel inhibits cytochrome oxidase by reacting with heme a3 increases membrane proton permeability blocks electron transfer at NADH dehydrogenase (NAD-Q oxidoreductase) binds to inward-facing site of ATP-ADP translocase Classify the metabolic poisons as electron transport inhibitors, uncoupling agents, ATP synthase inhibitors, or transport inhibitors. Electron transport inhibitors Uncoupling agents, ionophores ATP synthase inhibitors Transport inhibitors rotenone oligomycin cyanide bongkrekic acid FCCP
In the lab, metabolic poisons can be used to study ATP synthesis and oxygen consumption. Many of these poisons have - or have had - other uses, from diet aids to animal poisons to antibiotics. Poison oligomycin cyanide trifluorocarbonylcyanide phenylhydrazone (FCCP) rotenone bongkrekic acid Action binds to Fo and blocks the proton channel inhibits cytochrome oxidase by reacting with heme a3 increases membrane proton permeability blocks electron transfer at NADH dehydrogenase (NAD-Q oxidoreductase) binds to inward-facing site of ATP-ADP translocase Classify the metabolic poisons as electron transport inhibitors, uncoupling agents, ATP synthase inhibitors, or transport inhibitors. Electron transport inhibitors Uncoupling agents, ionophores ATP synthase inhibitors Transport inhibitors rotenone oligomycin cyanide bongkrekic acid FCCP
Biology Today and Tomorrow without Physiology (MindTap Course List)
5th Edition
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Christine Evers, Lisa Starr
Chapter4: Energy And Metabolism
Section: Chapter Questions
Problem 5CT
Related questions
Question
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps
Recommended textbooks for you
Biology Today and Tomorrow without Physiology (Mi…
Biology
ISBN:
9781305117396
Author:
Cecie Starr, Christine Evers, Lisa Starr
Publisher:
Cengage Learning
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Biology Today and Tomorrow without Physiology (Mi…
Biology
ISBN:
9781305117396
Author:
Cecie Starr, Christine Evers, Lisa Starr
Publisher:
Cengage Learning
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning