
In 1976, a team of chemists in the United Kingdom was developing new insecticides by modifying sugars with chlorine (Cl2), phosgene (Cl2CO), and other toxic gases. One young Member of the team misunderstood his verbal instructions to “test” a newly made candidate substance. He thought he had been told to “taste” it. Luckily for him, the substance was not toxic, but it was very sweet. It became the food additive sucralose.
Sucralose has three chlorine atoms substituted for three hydroxyl groups of sucrose (table sugar). It binds so strongly to the sweet-taste receptors on the tongue that the human brain perceives it as 600 times sweeter than sucrose. Sucralose was originally marketed as an artificial sweetener called Splenda”, but it is now available under several other brand names.
Researchers investigated whether the body recognizes sucralose as a carbohydrate. They began by feeding sucralose labeled with 14C to volunteers. Analysis of the radioactive molecules in the volunteers’ urine and feces showed that 92.8 percent of the sucralose passed through the body without being altered. Many people are worried that the chlorine atoms impart toxicity to sucralose. How would you respond to that concern?

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Chapter 3 Solutions
BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
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- I’m struggling with this topic and would really appreciate your help. I need to hand-draw a diagram and explain the process of sexual differentiation in humans, including structures, hormones, enzymes, and other details. Could you also make sure to include these terms in the explanation? • Gonads • Wolffian ducts • Müllerian ducts • Testes • Testosterone • Anti-Müllerian Hormone (AMH) • Epididymis • Vas deferens • Seminal vesicles • 5-alpha reductase • DHT • Penis • Scrotum • Ovaries • Uterus • Fallopian tubes • Vagina • Clitoris • Labia Thank you so much for your help!arrow_forwardOlder adults have unique challenges in terms of their nutrient needs and physiological changes. Some changes may make it difficult to consume a healthful diet, so it is important to identify strategies to help overcome these obstacles. From the list below, choose all the correct statements about changes in older adults. Select all that apply. Poor vision can make it difficult for older adults to get to a supermarket, and to prepare meals. With age, taste and visual perception decline. As people age, salivary production increases. In older adults with dysphagia, foods like creamy soups, applesauce, and yogurt are usually well tolerated. Lean body mass increases in older adults.arrow_forwardWhen physical activity increases, energy requirements increase also. Depending on the type, intensity, and duration of physical activity, the body’s requirements for certain macronutrients may change as well. From the list below, choose all the correct statements about the effects of increased physical activity or athletic training. Select all that apply. An athlete who weighs 70 kg (154 lb) should consume 420 to 700 g of carbohydrate per day. How much additional energy an athlete needs depends on the specific activity the athlete engages in and the frequency of the activity. Those participating in vigorous exercise should restrict their fat intake to less than 15%% of total energy intake. Athletes who are following energy-restricted diets are at risk for consuming insufficient protein. The recommendation to limit saturated fat intake to less than 10%% of total energy intake does not apply to athletes or those who regularly engage in vigorous physical activity.arrow_forward
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- the direct output from molecular replacement is a coordinate file showing the orientation of the unknown target protein in the unit cell. true or false?arrow_forwardDid your intake of vitamin C meet or come very close to the recommended amount? yes noarrow_forwardWhich of the following statements about hydration is true? Absence of thirst is a reliable indication that an individual is adequately hydrated. All of these statements are true. Although a popular way to monitor hydration status, weighing yourself before and after intensive physical activity is not a reliable method to monitor hydration. Urine that is the color of apple juice indicates dehydration. I don't know yetarrow_forward
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