Q.5 Propose a retrosynthesis and forward synthesis of the targeted molecule using the provided starting materials. Any reagents (organic or inorganic) can be used, and you may use any of the starting materials more than once along with any additional reagents. Note: all carbon atoms in the product must come from the starting materials provided. BrCH2CH2CH2CH CH2 CH3
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- Q.1 What are the sequences of the tetranucleotide products in panels I and II? Write out each sequence so that the initial nucleotide is on the left and the fourth (i. e. the last nucleotide incorporated) is on the right. Then label the 5' to 3' ends of each tetranucleotide. I P. IIThe questions are on the image.ii
- Which of the following statements regarding Anfinsen's denaturing experiments with ribonuclease A are valid? (i) Exposing the denatured protein to air oxidation and then dialysis to remove urea restored the protein to its original functionality. (ii) Removing urea by dialysis and then allowing air oxidation of the denatured protein restored the protein to its original functionality. (iii) Denaturing the protein with both urea and β-mercaptoethanol yielded an inactive protein. (iv) Protein folding is determined by its primary sequence.. Explain why DNA is stable in the presence of alkali (0.3 M KOH), while RNA is quantitatively degraded to 2'- and 3'-nucleoside monophosphates under these conditions.1) Provide a stepwise, arrow-pushing mechanism for the following transformation. You may use general acid and base as necessary. Feel free to abbreviate structures as needed. why مسلسلند OH SCOA Lyase TPP H + Hi SCOA
- Please asapCheto. Seven E. coli mutants were isolated. The activity ofthe enzyme β-galactosidase produced by cells containing each mutation alone or in combination with othermutations was measured when the cells were grown inmedium with different carbon sources.Lactose +Glycerol Lactose GlucoseWild type 0 1000 10Mutant 1 0 10 10Mutant 2 0 10 10Mutant 3 0 0 0Mutant 4 0 0 0Mutant 5 1000 1000 10Mutant 6 1000 1000 10Mutant 7 0 1000 10F′ lac from mutant 0 1000 101/ mutant 3F′ lac from mutant 0 10 102/ mutant 3Mutants 3 + 7 0 1000 10Mutants 4 + 7 0 0 0Mutants 5 + 7 0 1000 10Mutants 6 + 7 1000 1000 10Assume that each of the seven mutations is one andonly one of the genetic lesions in the following list.Identify the type of alteration each mutation represents.a. superrepressorb. operator deletionc. nonsense (amber) suppressor tRNA gene (assumethat the suppressor tRNA is 100% efficient in suppressing amber mutations)d. defective CRP–cAMP binding sitee. nonsense (amber) mutation in the β-galactosidase genef.…