Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 9, Problem 14RQ
What is the function of a phosphatase?
- A phosphatase removes phosphorylated amino acids from proteins.
- A phosphatase removes the phosphate group from phosphorylated amino acid residues in a protein.
- A phosphatase phosphorylates serine, threonine, and tyrosine residues.
- A phosphatase degrades second messengers in the cell.
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Kinases are enzymes responsible for transferring the terminal phosphate of ATP to the side chains of serines, threonines, and tyrosines in proteins. This is called phosphorylation. Many kinases require autophosphorylation before they can phosphorylate other targets. Discuss how phosphorylation of Ser, Thr, and Tyr changes their chemical properties and how phosphorylation of a kinase might help make it active for other substrates..
Select statements that accurately describe receptor tyrosine kinases (RTKs).
Some RTKs are dimeric in the presence of a ligand.
GTPase activity is required for autophosphorylation (cross-phosphorylation).
The structure includes a transmembrane helix.
The intracellular domain has kinase domains.
The a subunit contains seven a helices that span the membrane.
A ligand binds to the extracellular domain.
Which of the following catalyzes the cutting of PIP2 into 2 moles of IP3 and diacylglycerol in cell signaling?
a) Phosphodiesterase C
b) Phosphokinase C
c) Phospholipase C
d) Lipokinase
Chapter 9 Solutions
Biology 2e
Ch. 9 - Figure 9.8 HER2 is a receptor tyrosine kinase. In...Ch. 9 - Figure 9.10 In certain cancers, the GTPase...Ch. 9 - Figure 9.17 Which of the following statements...Ch. 9 - Figure 9.18 What advantage might biofilm...Ch. 9 - What property prevents the ligands of cell-surface...Ch. 9 - The secretion of hormones by the pituitary gland...Ch. 9 - Why are ion channels necessary to transport ions...Ch. 9 - Endocrine signals are transmitted more slowly than...Ch. 9 - A scientist notices that when she adds a small,...Ch. 9 - Where do DAG and IP3 originate? They are formed by...
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