Biology 2e
Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 9, Problem 14RQ

What is the function of a phosphatase?

  1. A phosphatase removes phosphorylated amino acids from proteins.
  2. A phosphatase removes the phosphate group from phosphorylated amino acid residues in a protein.
  3. A phosphatase phosphorylates serine, threonine, and tyrosine residues.
  4. A phosphatase degrades second messengers in the cell.

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Select statements that accurately describe receptor tyrosine kinases (RTKs). Some RTKs are dimeric in the presence of a ligand. GTPase activity is required for autophosphorylation (cross-phosphorylation). The structure includes a transmembrane helix. The intracellular domain has kinase domains. The a subunit contains seven a helices that span the membrane. A ligand binds to the extracellular domain.
Histamine is a chemical substance released in inflammatory and allergic response. The histamine H1 receptor is a G protein-coupled receptor that activates phospholipase C in response to the binding of histamine. Arrange the data below showing the process of histamine signal transduction from the H1 receptor. Calcium ions flow through ligand-gated ion channel. Phosphorylation cascade leads to the activation of a cellular response. Calcioum ions activate a protein, leading to a cellular response. Enzyme cleaves PIP2, forming DAG and IP3. Calcium iom concentration increases in the cytosol. IP3 binds to a ligand-gated ion channel in thw ER membrane.
The activity of an enzyme can be altered when it becomes negatively charged due to: phosphate removal by a kinase, which is called dephosphorylation phosphate removal by a phosphatase, which is called dephosphorylation phosphate removal by a kinase, which is called phosphorylation phosphate addition by a phosphatase, which is called dephosphorylation phosphate addition by a kinase, which is called phosphorylation

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