Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 9, Problem 10RQ
Where do DAG and IP3 originate?
- They are formed by phosphorylation of cAMP.'
- They are ligands expressed by signaling cells.
- They are hormones that diffuse through the plasma membrane to stimulate protein production.
- They are the cleavage products of the inositol phospholipid, PIP2.
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Chapter 9 Solutions
Biology 2e
Ch. 9 - Figure 9.8 HER2 is a receptor tyrosine kinase. In...Ch. 9 - Figure 9.10 In certain cancers, the GTPase...Ch. 9 - Figure 9.17 Which of the following statements...Ch. 9 - Figure 9.18 What advantage might biofilm...Ch. 9 - What property prevents the ligands of cell-surface...Ch. 9 - The secretion of hormones by the pituitary gland...Ch. 9 - Why are ion channels necessary to transport ions...Ch. 9 - Endocrine signals are transmitted more slowly than...Ch. 9 - A scientist notices that when she adds a small,...Ch. 9 - Where do DAG and IP3 originate? They are formed by...
Ch. 9 - What property enables the residues of the amino...Ch. 9 - Histamine binds to the H1 G-protein-linked...Ch. 9 - A scientist observes a mutation in the...Ch. 9 - What is the function of a phosphatase? A...Ch. 9 - How does NF-kB induce gene expression? A small,...Ch. 9 - Apoptosis can occur in a cell when the cell is...Ch. 9 - What is the effect of an inhibitor binding an...Ch. 9 - How does PKC’s signaling role change in response...Ch. 9 - A scientist notices that a cancer cell line fails...Ch. 9 - Which type of molecule acts as a signaling...Ch. 9 - Quorum sensing is triggered to begin when...Ch. 9 - A doctor is researching new ways to treat biofilms...Ch. 9 - What is the difference between intracellular...Ch. 9 - How are the effects of paracrine signaling limited...Ch. 9 - What are the differences between internal...Ch. 9 - Cells grown in the laboratory are mixed with a dye...Ch. 9 - Insulin is a hormone that regulates blood sugar by...Ch. 9 - The same second messengers are used in many...Ch. 9 - What would happen if the intracellular domain of a...Ch. 9 - If a cell developed a mutation in its MAP2K1 gene...Ch. 9 - What is a possible result of a mutation in a...Ch. 9 - How does the extracellular matrix control the...Ch. 9 - A scientist notices that a cancer cell line shows...Ch. 9 - What characteristics make yeasts a good model for...Ch. 9 - Why is signaling in multicellular organisms more...Ch. 9 - Pseudomonas infections are very common in hospital...
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- Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway constriction associated with an allergic response. If a mutation in the associated G-protein’s alpha subunit prevented the hydrolysis of GTP how would the allergic response change? More severe allergic response compared to normal G-protein signaling. Less severe allergic response compared to normal G-protein signaling. No allergic response. No change compared to normal G-protein signaling.arrow_forward1) the Ga subunit has a mutation resulting in increased GTPase activity? Why is the GPCR referred to as a GEF? What would occur in G protein signalling ifarrow_forwardA mutated form of the α subunit of the heterotrimeric G protein has been identified; this form readily exchanges nucleotides even in the absence of an activated receptor. What would be the effect on a signaling pathway containing the mutated α subunit?arrow_forward
- Don't missarrow_forwardN Signal Sequence The schematic above depicts a protein with the indicated signaling sequences along its length. Based on these signaling sequences what type of protein is this? N-X-S/T there is not enough information to determine A secreted peptide hormone A lysosomal hydrolase A glycoproteinarrow_forwardCytokine receptors and tyrosine kinase receptors are similar in all of the following ways EXCEPT one. Which one is the exception? O They are both down-regulated by lysosomal degradation They both involve receptor exoplasmic domain dimerization They both result in an effector protein entering the nucleus O They both involve cytosolic domain phosphorylationarrow_forward
- 3 of 16 Which statement about the IP3 DAG pathway is false? O Diacylglycerol can act as a second messenger. Inositol trisphosphate can act as a second messenger. O Protein kinase C can phosphorylate a wide variety of proteins. O Inositol trisphosphate remains bound to the membrane after phospholipase C catalyzes its formation. Inositol trisphosphate can open ion channels in the membraņes of smooth endoplasmic reticulum, releasing calcium into the cytoplasm.arrow_forwardWhy do we need to identify and determine the function of every single molecule involved in cell signalling? Provide one concrete example of an application of an elucidated cascade of events in cell signalling. (The answer should be no less than 300 words)arrow_forwardPart Barrow_forward
- 46. Of the following signaling processes which one is NOT involved in cellular movement or cytoskeletal changes? (3) $ 50000 Ca Binding site catenin (2) CAP Daam1 ROCK Ras GTP Raf Dsh RhoA) SOS MEK (ERK)arrow_forward1. Plays an important role in intracellular signaling 2. helps maintain an erection in men 3. has a key role in glycoprotein synthesis 4. Helps control diabetes by reducing blood sugar and insulin resistance 5. facilitates absorption of minerals such as Potassium, Magnesium, and Calcium 6. removes toxic substances from the breakdown of muscle proteins during intensive exercise 7. has a synergistic effect with Vitamin E and Selenium 8. Needed to produce tryptophan 9. Protects myelin sheath 10. facilitates removal of heavy metals such as mercury Choices for the answers: A. Alanine B. Cysteine C. Glutamine D. Glutathione E. Glycine F. Serine G. Taurine H. Aspargine I. Aspartic Acid J. Proline K. L-arginine L. Tyrosinearrow_forwardWhich of the following regarding GPCR's is FALSE? GPCR ligand binding stimulates phosphorylation of the heterotrimeric G protein GPCR's have seven transmembrane domains The alpha subunit of the heterotrimeric G protein is active in its GTP bound state The beta-gamma subunit of the heterotrimeric G protein performs signaling functionsarrow_forward
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