Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 12P

On the DrosophilaX chromosome, the dominant allele y+ produces gray body color and the recessive allele y producesyellow body. This gene is linked to one controlling full eye shape by a dominant allele lz+ and lozenge eye shape with arecessive allele lz . These genes recombine with a frequency of approximately 28% . The Lz gene is linked to gene F controlling bristle form, where the dominant is long bristlesand the recessive is forked bristles. The Lz and F genes recombine with a frequency of approximately 32% .

a. Using any genotypes you choose, design two separatecrosses, one to test recombination between genes Y and Lz and the second between genes Lz and F. Assume 1000 progeny are produced by each cross, and give thenumber of progeny in each outcome category. (In setting up your crosses, remember that Drosophila males do not undergo recombination.)

b. Can any cross reveal genetic linkage between gene Y and gene F? Why or why not?

c. Why is “independent assortment” the genetic term thatbest describes the observations of a genetic cross between gene Y and gene F?

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In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked.    A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3            pld     rmp    dwp 428        pld    rmp      + 427         +       +       dwp 48           +     rmp      + 47         pld      +       dwp 23         pld      +        + 2             +       +        + 22           +     rmp    dwp   What is the order and map distance between these three alleles?
In the fruit fly Drosophila melanogaster, the following genes and mutations are known:Wing size: recessive allele for tiny wings t; dominantallele for normal wings T.Eye shape: recessive allele for narrow eyes n;dominant allele for normal (oval) eyes N.For each of the four following crosses, give thegenotypes of each of the parents.Male FemaleWings Eyes Wings Eyes Offspring1 tiny oval × tiny oval 78 tiny wings, oval eyes24 tiny wings, narrow eyes2 normal narrow × tiny oval 45 normal wings, oval eyes40 normal wings, narrow eyes38 tiny wings, oval eyes44 tiny wings, narrow eyes3 normal narrow × normal oval 35 normal wings, oval eyes29 normal wings, narrow eyes10 tiny wings, oval eyes11 tiny wings, narrow eyes4 normal narrow × normal oval 62 normal wings, oval eyes19 tiny wings, oval eyes
In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+  b  c                            460a  +  +                           450a  b  c                              32+ + +                              38a  + c                              11+ b +                               9 No other phenotypes were observed.(a) What is the genotypic arrangement of the alleles ofthese genes on the X chromosome of the female?

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Genetic Analysis: An Integrated Approach (3rd Edition)

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