Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 15P

Three dominant traits of corn seedlings, tunicate seed( T– ), glossy appearance ( G– ), and liguled stem ( L– ), arestudied along with their recessive counterparts, nontunicate ( tt ), nonglossy ( gg ), and liguleless( ll ). A trihybrid plantwith the three dominant traits is crossed to a nontunicate, nonglossy, liguleless plant. Kernels on ears of progenyplants are scored for the traits, with the following results:

P h e n o t y p e N u m b e r T u n i c a t e , g l o s s y , l i g u l e d 102 T u n i c a t e , g l o s s y , l i g u l e l e s s 106 T u n i c a t e , n o n g l o s s y , l i g u l e d 18 T u n i c a t e , n o n g l o s s y , l i g u l e l e s s 20 N o n t u n i c a t e , g l o s s y , l i g u l e d 22 N o n t u n i c a t e , g l o s s y , l i g u l e l e s s 23 N o n t u n i c a t e , n o n g l o s s y , l i g u l e d 99 N o n t u n i c a t e , n o n g l o s s y , l i g u l e l e s s 110 500

a. Is there evidence of genetic linkage among any of thesegene pairs? If so, identify the evidence.

b. Is there evidence of independent assortment among any of these gene pairs? If so, identify the evidence.

c. Using the gene symbols given above, write the genotypes of F1 and F2 plants.

d. If evidence of linkage is present, calculate the recombination fraction(s) from the data presented.

e. Could all three genes be carried on the same chromosome? Discuss why or why not.

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calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data.show solving and answer a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist t1/2,absorb f) t1/2,elim   k) apparent central compartment volume (V1,app) p) total AUC (using short cut method) apparent volume of distribution based on AUC (VAUC,app)  apparent clearance (CLapp)   absolute bioavailabilty of oral route ( AUCiv =116ml)
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AaBbCc X AaBbCc individuals are crossed. What is the probability of their offspring having a genotype AABBCC?

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Genetic Analysis: An Integrated Approach (3rd Edition)

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