Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 37P
For six genes known to be linked on chromosme
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Students have asked these similar questions
If 2 genes on the same chromosome have a recombination frequency of .01, what is the genetic distance from each other in map units?
The following recombinant frequencies were found between genes A, B, C, D,
and E. Determine the order of these genes on the chromosome and draw a
linkage map of this chromosome with the map units labeled.
А, С: 10%
А, D: 30%
А, Е: 6%
В, С: 4%
В, D: 16%
В, Е: 20%
C, D: 20%
Recombination frequencies between four genetically-linked loci in corn are shown in the following table:
Loci Recombination Frequency (%)
L and Q 20
Q and R 50
R and L 30
Q and W 13
L and W 7
What is the order of the genes on the chromosome?
(note: The same answer can be represented forward or backwards. e.g. A B C D = D C B A)
LQWR
RQWL
LRQW
QRLW
RLWQ
Chapter 5 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 5 - For parts a, b, and c, draw a diagram illustrating...Ch. 5 - 5.2 In a diploid species of plant, the genes for...Ch. 5 - A pure-breeding tall plant producing oval fruit as...Ch. 5 - 5.4 Genes E and H are syntenic in an experimental...Ch. 5 - In tomato plants, purple leaf color is controlled...Ch. 5 - 5.6 In Drosophila, the map positions of genes are...Ch. 5 - 5.7 Genes A, B, and C are linked on a chromosome...Ch. 5 - Gene G recombines with gene T at a frequency of...Ch. 5 - Genes A, B, C, D, and E are linked on a...Ch. 5 - Syntenic genes can assort independently. Explain...
Ch. 5 - 5.11 The recombination frequency between linked...Ch. 5 - On the DrosophilaX chromosome, the dominant allele...Ch. 5 - Researchers cross a corn plant that is pure -...Ch. 5 - 5.14 syndrome is an autosomal disorder affecting...Ch. 5 - 5.15 Three dominant traits of corn seedlings,...Ch. 5 - 5.16 In a diploid plant species, an with the...Ch. 5 - Prob. 17PCh. 5 - The Rh blood group in humans is determined by a...Ch. 5 - 5.19 Genetic linkage mapping for a large number of...Ch. 5 - 5.20 with the genotype form tetrads in the...Ch. 5 -
Gene and gene are genetically linked. Answer...Ch. 5 -
T. H. Morgan’s data on eye color and wing form,...Ch. 5 - Prob. 23PCh. 5 -
The boss in your laboratory has just heard of a...Ch. 5 - In rabbits, chocolate-colored fur (w+) is dominant...Ch. 5 - Prob. 26PCh. 5 - 5.27 In tomatoes, the allele for tall plant height...Ch. 5 - 5.28 Neurofibromatosis is an autosomal dominant...Ch. 5 - A 2006 genetic study of a large American family...Ch. 5 - 5.30 A experiment examining potential genetic...Ch. 5 - A genetic study of an early onset form of heart...Ch. 5 - In experiments published in 1918 that sought to...Ch. 5 - DNA sequence for 10 individuals are Identify the...Ch. 5 - 5.34 The accompanying pedigree below shows a...Ch. 5 - 5.35 Based on previous family studies, an...Ch. 5 - Divide a clean sheet of paper into four quadrant...Ch. 5 - 5.37 For six genes known to be linked on chromosme...
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- In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable order of these genes on the chromosome? b 0 cn 90 rb 3.5 6.5 0 vg 19 9.0 16 0 b cn rb vg The numbers in the boxes are the recombination frequencies in between the genes (in percent). O b-rb-cn-vg O vg-cn-b-rb Orb-cn-vg-b b = black body cn = cinnabar eyes rb = reduced bristles vg = vestigial wings O vg-b-rb-cnarrow_forwardTo determine the recombination frequency between body color and wing genes in flies, you perform several crosses where you cross an F1 having red body and smooth wings with a yellow-bodied, crinkle-winged fly. You get the following results. What is the distance between the genes for body color and wing surface in map units?arrow_forwardIn a series of mapping experiments, the recombination frequencies for four different linked genes were determined as follows: vg= vestigial wings vg-b = 19 cn= cinnabar eyes vg-cn = 9 rb= reduced bristles vg-rb = 16 b= black body rb-b = 3.5 rb-cn = 6.5 cn-b = 9 Please map the genes in order on a chromosome. Which two genes are the closest together? What is your evidence?arrow_forward
- Recombination frequencies between four genetically-linked loci in corn are shown in the following table: Loci Recombination Frequency (%) R and Q 45 W and Q 60 R and W 15 Q and L 10 L and R 35 What is the order of the genes on the chromosome? (note: The same answer can be represented forward or backwards. e.g. A B C D = D C B A) RQWL LQWR QWLR QRLW WRLQarrow_forwardPlease label the tetrad type in the table as PD (parental ditype), NPD (non parental ditype) or T (tetratype) and answer the following questions a) Are the genes linked? Please explain SPECIFICALLY how you can distinguish between linked and unlinked genes in this instance. b) If the two genes are linked, calculate the % recombination between ser and thr. Show the formula used, as well as all of your calculations. c) Draw a single map illustrating the arrangement of the two genes on the chromosome with respect to each other and to the centromere of the chromosome. Make sure to map ALL three distancesarrow_forwardYou are studying four linked genes located on chromosome 2 in the fruit fly Drosophila melanogaster: adp (which contributes to obesity), b (which contributes to body color), pr (which contributes to metabolism), and vg (which contributes to wing formation). A series of crosses between pair-wise combinations of these mutations yielded the following recombination frequencies between the indicated loci: pr and adp 9% adp and b 6% pr and b 3% vg and b 10% vg and pr 7% What is the genetic distance in map units (cM) between the adp and vg loci? 16 9 6 4arrow_forward
- In an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of the haploid fungus Neurospora crassa (n = 7) moves slowly but eventually forms seven bands, which represent DNA fractions that are of different sizes and hence have moved at different speeds. These bands are presumed to be the seven chromosomes. How would you show which band corresponds to which chromosome?arrow_forwardConsider two loci A and B that are 30 cM apart on chromosome 1 in the fruit fly. A paracentric inversion is found to span about half of the distance between these loci, but not include either A or B. What is the approximate recombination frequency expected for these loci in … flies that are heterozygous for this inversion? RF(A-B) for heterozygous flies is … flies that are homozygous for this inversion? RF(A-B) for homozygous flies is …arrow_forwardA yeast geneticist irradiates haploid cells of a strain that is an adenine-requiring auxotrophic mutant, caused by mutation of the gene ade1. Millions of the irradiated cells are plated on minimal medium, and a small number of cells divide and produce prototrophic colonies. These colonies are crossed individually with a wildtype strain. Two types of results are obtained:(1) prototroph × wild type : progeny all prototrophic(2) prototroph × wild type : progeny 75% prototrophic, 25% adenine-requiring auxotrophsa. Explain the difference between these two types of results.b. Write the genotypes of the prototrophs in each case.c. What progeny phenotypes and ratios do you predict from crossing a prototroph of type 2 by the original ade1auxotroph?arrow_forward
- Alleles of genes A and B were analyzed in Neurospora according to the cross shown below. Ordered tetrads are summarized in each horizontal row with the number of tetrads in each category listed alongside. A) Analyze the data to determine the recombination frequency (RF) between A and B, along with any additional information that is available from this data. B) Draw a map of the chromosome or chromosomes with appropriate map distances. C) Use the Perkins formula to reanalyze any relationship between A and B.arrow_forwardRecombination frequencies between three loci in corn are shown in the following table: Loci Recombination frequency (%) R and W2 17 R and L2 35 W2 and L2 18 What is the order of the genes on the chromosome?arrow_forwardIn D. melanogaster, reduced bristles (rd), cinnabar eyes (cn), and vestigial wings (vg) are recessive traits located on chromosome II in that order. The distance between rd and cn is 7 cM and the distance between cn and vg is 9 cM. The CoC for this chromosome is 0.9. A true-breeding female expressing cinnabar eyes and vestigial wings is crossed to a true-breeding male expressing reduced bristles. The F1 are wild type. An F1 female is then test crossed to a male expressing all three traits. Among the F2 progeny, how often would you expect to observe flies expressing only cinnabar eyes? Using the same information from above, among the F2 progeny, how often would you expect to observe flies expressing only vestigial wings?arrow_forward
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