Interpretation:
An efficient synthesis for the given transformation has to be predicted. The given reaction is shown as,
Concept Introduction:
Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors.
Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho-para directing.
Halogens are deactivators that are ortho-para directing.
Friedel-Crafts Acylation: This Lewis acid-catalyzed electrophilic
The reduction of
Nitration: In nitration reaction, one nitro group
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Organic Chemistry As a Second Language: Second Semester Topics
- Solve with explanation needarrow_forwardPropose a synthesis for the transformations shown below (no mechanisms needed, just products/intermediates and reagents). You will get full credit if you figure out two out of three. Clearly indicate which two you want us to grade.arrow_forwardUsing two equivalents of butane as your only source of carbon, show how you could synthesize the compound displayed below via a Grignard synthesis. OH Draw your synthesis on paper or on a tablet, showing your starting materials, reagents, intermediates, and your final product in correct order. You can use any other reagents that we learned about, provided that none of them add carbon atoms to the final structure. Sign your name to indicate that you did it yourself. Snap a photo and upload it as a jpg or pdf file.arrow_forward
- Continue the synthesis by selecting the reagents necessary for the next transformation shown. ? Br The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A B C EtONa HBr, ROOR H₂, Lindlar's cat. D E F HBr HC=CNa H₂, Pd G H I 1) 03; 2) DMS 1) NaNH2; 2) EtBr 1) R₂BH; 2) H₂O2, NaOHarrow_forwardNeed help on finding the order of reagents to produce the product.arrow_forwardCan you please help how to answer this question with elaborate step?arrow_forward
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- Give detailed Solution with explanation needed..give correct answer pleasearrow_forwardChemistry Perform the following syntheses. Use the retrosynthetic analysis shown in the example. Be certain to show all of your reasoning which leads to your final answer. All can be accomplished in 2-3 steps. Show all reagents and intermediate products. All reactions necessary to complete these syntheses can be found in Chapters 6, 7, and 9. Also, look at the reactions in Part I. Remember, start from the target product and go one-step back to get started. HO CH3 Br <- HC EC-arrow_forwardConstruct a three-step synthesis of 3-bromocyclopentene from cyclopentane. Drag the appropriate items into the bins. Note that each bin should hold only one item, and not all reagents and structures will be used. Reagent 3 Reagent 2 Reagent 1 Final product Reactant Step 1 product Step 2 product (cyclopentane) (3-bromocyclopentene) NBS ROOR HBr HBr ROOR Br Br2 Br2 Hzо hv Br Br Br Br Br (CH3)3CO Karrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning