An efficient synthesis for the given transformation has to be predicted. The given reaction is shown as, Concept Introduction: Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors. Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho-para directing. Halogens are deactivators that are ortho-para directing. In a reaction, fuming sulfuric acid is used to introduce sulfonic groups in a compound (sulfonation) or sometimes used as blocking groups. Chlorination: A reaction in which a chlorine atom is introduced to the compound. In a reaction, sulfonic acid group can be removed from a compound by treating it with dilute sulfuric acid (desulfonation). Friedel-Crafts Alkylation: This Lewis acid-catalyzed electrophilic aromatic replacement that allows the synthesis of alkylated products by means of the reaction of arenes through alkyl halides or alkenes.

Question

Want to see the full answer?

Answer 1

Question

Chapter 4.9, Problem 4.96P

Interpretation Introduction

Interpretation:

An efficient synthesis for the given transformation has to be predicted. The given reaction is shown as,

Concept Introduction:

Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors.

Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho-para directing.

Halogens are deactivators that are ortho-para directing.

In a reaction, fuming sulfuric acid is used to introduce sulfonic groups in a compound (sulfonation) or sometimes used as blocking groups.

Chlorination: A reaction in which a chlorine atom is introduced to the compound.

In a reaction, sulfonic acid group can be removed from a compound by treating it with dilute sulfuric acid (desulfonation).

Friedel-Crafts Alkylation: This Lewis acid-catalyzed electrophilic aromatic replacement that allows the synthesis of alkylated products by means of the reaction of arenes through alkyl halides or alkenes.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

111 Carbonyl Chem Choosing reagants for a Wittig reaction What would be the best choices for the missing reagents 1 and 3 in this synthesis? 1. PPh3 3 1 2 2. n-BuLi • Draw the missing reagents in the drawing area below. You can draw them in any arrangement you like. Do not draw the missing reagent 2. If you draw 1 correctly, we'll know what it is. • Note: if one of your reagents needs to contain a halogen, use bromine. Explanation Check Click and drag to start drawing a structure. × ©2025 McGraw Hill LLC. All Rights Reserved. Terms of Use

A student proposes the transformation below in one step of an organic synthesis. There may be one or more reactants missing from the left-hand side, but there are no products missing from the right-hand side. There may also be catalysts, small inorganic reagents, and other important reaction conditions missing from the arrow. • Is the student's transformation possible? If not, check the box under the drawing area. . If the student's transformation is possible, then complete the reaction by adding any missing reactants to the left-hand side, and adding required catalysts, inorganic reagents, or other important reaction conditions above and below the arrow. • You do not need to balance the reaction, but be sure every important organic reactant or product is shown. + T X O O лет-ле HO OH HO OH This transformation can't be done in one step.

Determine the structures of the missing organic molecules in the following reaction: X+H₂O H* H+ Y OH OH Note: Molecules that share the same letter have the exact same structure. In the drawing area below, draw the skeletal ("line") structures of the missing organic molecules X and Y. You may draw the structures in any arrangement that you like, so long as they aren't touching. Click and drag to start drawing a structure. X S