Interpretation:
The expected directing effects that would be observed if the given compound undergoes an electrophilic
Concept Introduction:
Electrophilic substitution reaction is a type of reaction in which a particular group or atom in a compound is replaced by electrophile. An electrophile is a species that is deficient of electrons
Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors.
Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho-para directing.
Halogens are deactivators that are ortho-para directing.
Want to see the full answer?
Check out a sample textbook solutionChapter 4 Solutions
Organic Chemistry As a Second Language: Second Semester Topics
- The following molecule undergoes an intramolecular reaction in the presence of pyrrolidinium acetate, the protonated form of pyrrolidine. Draw the product of this reaction, assuming that a dehydration reaction takes place.arrow_forwardEnamines can serve as enolate surrogates in reactions at the a-carbon. In the reaction sequence, the structures of the enamine addition product – the initial iminium and its neutral tautomer – are shown. Draw the structures of the enamine and alkyl bromide reactants that would combine to form these intermediates, and draw the structure of the final product, obtained via hydrolysis of the neutral intermediate. iminium intermediate neutral intermediate tautomerization N. Reactants H20 hydrolysis product Draw the enamine and alkyl bromide reactants. Draw the hydrolysis product. ZIarrow_forwardShow how acid derivatives hydrolyze to carboxylic acids under either acidic or basicconditions. Explain why some acid derivatives (amides, for example) require muchstronger conditions for hydrolysis than other derivatives.arrow_forward
- help please answer in text form with proper workings and explanation for each and every part and steps with concept and introduction no AI no copy paste remember answer must be in proper format with all workingarrow_forwardPropose a sequence of reactions to synthesize the target compound below from the indicated starting materials. You may use any other organic and/or inorganic reagents necessary to complete your synthesis, but all carbon atoms in the target must be derived from the starting materials specified. It is only necessary to give overall transformations in answering this question. Please DO NOT provide curved arrow mechanisms for the reactions that you use. Prepare from and and CH;CH2OH HO, TARGET as the only sources of C atoms in the targetarrow_forwardELO ots Propose a sequence of reactions to synthesize the target compound below from the indicated starting materials. You may use any other organic and/or inorganic reagents necessary to complete your synthesis, but all carbon atoms in the target must be derived from the starting materials specified. It is only necessary to give overall transformations in answering this question. Please DO NOT provide curved arrow mechanisms for the reactions that you use. Please note that all carbon atoms in the target must originate from any of the indicated starting materials. You may not need to use all of these starting materials to complete the synthesis. OH CH3I CH;CH,Br CH;CH2CH,Br EtO `CH3 TARGET 3-Ethyl-2-hexanol You may only use these compounds as necessary as the sources for all C atoms in the target Your ansa ded in the single ndf file that vou upload for the "Exam 5 File Submission"arrow_forward
- Propose a sequence of reactions to synthesize the target compound below from the indicated starting material. You may use any other organic and/or inorganic reagents necessary to complete your synthesis, but all carbon atoms in the target must be derived from the starting material specified. It is only necessary to give overall transformations in answering this question. Please DO NOT provide curved arrow mechanisms for the reactions that you use. Prepare from as the only source of C atoms in the target OEt TARGET Your =arrow_forwardPropose a sequence of reactions to synthesize the target compound below from the indicated starting materials. You may use any other organic and/or inorganic reagents necessary to complete your synthesis, but all carbon atoms in the target must be derived from the starting materials specified. It is only necessary to give overall transformations in answering this question. Please DO NOT provide curved arrow mechanisms for the reactions that you use. Prepare from and CH3l НО. НО, TARGET as the only sources of C atoms in the targetarrow_forwardReductive amination is one of the best methods to prepare amines. However, direct alkylation with alkyl halides can be used to synthesize substituted amines. Can you identify potential problem(s) when alkylating agents are used?arrow_forward
- Highlight each of the positions on the benzene ring that you expect will be most likely to react by electrophilic aromatic substitution. Am I correct?arrow_forwardDevelop the mechanism of the following electrophilic aromatic substitutionarrow_forwardSelect the conditions in which elimination/condensation is most likely to occur. Note that only one of these needs to be present for elimination/condensation to be likely. Protic solvent Aprotic solvent Acidic conditions Basic conditions Cold Hot Shorter reaction time Longer reaction timearrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningEBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT