You are studying pancreatic cancer have matched samples of tumor and healthy pancreatic tissue. You use a microarray to determine gene expression differences between these two sample. You label the healthy tissue cDNA with red fluorescnce and the tumor cDNA with green. You apply these cDNAs to your chip. Beta-actin is a housekeeping gene required for cell structure. What color would you expect the spot for this gene to be?    a. Red   b. Green   c. Yellow   d. No color   e. None of the above

Q: A mouse gene was identified and determined to be required for formation of heart muscle. A gene with…

A: Almost all species have DNA as their genetic material.

Q: Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that…

A: Stem cells are defined by their ability to self-renew as well as differentiate into a variety of…

Q: The p53 gene was discovered in 1979, but it was not clear whether the gene functioned as an oncogene…

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Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Induced pluripotent stem cells (iPS) is a type of stem cell(pluripotent) in nature that is derived…

Q: Occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are…

A: CRISPR stands for Clustered regularly interspaced short palindromic repeats. It is a system of…

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Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

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A: Genome editing:It is also known as gene editing or genome engineering. It is a type of genetic…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: DMC1 SPS1 DIT1 SPS100 fold repressed >20 1:1 fold induced x10x >20

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Q: graduate student wants to isolate cells from a patient and grow them perpetually in culture to study…

A: The correct answers are as follows- A. Telomerase C. MDM2  A graduate student wants to isolate cells…

Q: For a gene to be cancer-inducing, both copies of the gene must be affected, explain it with example.

A: Cancer inducing gene The gene having the potential to cause cancer are called as cancer inducing…

Q: cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the…

A: HAT stands for Histone acetyl transferase. The LOF refers to the loss of function mutation. If a…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

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A: Repair and closure (12001 - 13160)

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Q: You treat some cancer cells with a new therapeutic that you hope will kill them. You run an MTT…

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Q: You are analyzing the activity of the protein p53 in two different cell types. You notice that p53…

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Q: You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All…

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Q: On the image, you can see the results of a DNA microarray used for cancer prognosis, where tissue…

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Q: You are studying celiacs disease and have identified a potential gene for the disease using linkage…

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Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…

A: It is an uncontrollable cell division that get metastasized into surrounding tissues.

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.