RASL11A gene is a tumor suppressor gene associated with spontaneous tumor shrinkage in Tasmanian Devils.  In those tumors that shrink, the expression of RASL11A is: Group of answer choices a. upregulated compared to the expression in tumors that proliferate. b. downregulated compared to the expression in tumors that proliferate. c. the same as in those tumors the expression in tumors that proliferate.

Q: for question 1, choose wheater each choice is either tumor suppressor or proto oncogene\ for…

A: Proto-oncogenes and tumor suppressor genes are two types of genes that play important roles in the…

Q: Gene expression array technology has been used to do which of the following (select all that apply)?…

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Q: What would you expect to observe if you engineered a chimeric nuclear receptor superfamily protein…

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Q: (Theme 5) Below are data from Jimenez et al (2022) depicting cellular expression patterns of the…

A: The question pertains to the intriguing phenomenon of cellular expression patterns, specifically…

Q: a way in which proto-oncogenes can change to become genes that induce cancer?

A: A proto-oncogene is a normal gene that can turn into an oncogene due to mutations or increased…

Q: State true or false, giving a brief justification: a. An enhancer is a type of regulatory element.…

A: Gene regulation is the process of turning genes on and off. During early development, cells begin to…

Q: After the initial Actualization of the Cit+ phenotype, there was another alteration to the A-3…

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Q: The figure below summarizes the results of an experiment evaluating the role of Ku80 gene DNA…

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Q: they argued that promoter switching may be correlated with cancer development and progression…

A: A DNA (deoxyribonucleic acid) sequence where the protein binds and initiates the transcription of…

Q: Which of the following statements are true about the rate of mutation in tumor cells (select all…

A: Chromosome rearrangements, which occur at high rates due to aneuploidy, an aberrant chromosome…

Q: Mutations in three broad classes of genes have been implicated in the onset of cancer. Can you…

A: A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic…

Q: Which of the following statements about qPCR is true?   a. The Ct value is generally directly…

A: qCR or Quantitative PCR is the technique which allows the measurement of expression levels by…

Q: A SNP array has identified a mutation in a tumor suppressor in a patient’s cancerous tumor. A drug…

A: Introduction:In the realm of personalized medicine, the identification of specific mutations within…

Q: Activation of p53 during cellular stress will generally Select one: o a. Increase transcription of…

A: P553 is a tumor suppressor gene.

Q: graduate student wants to isolate cells from a patient and grow them perpetually in culture to study…

A: The correct answers are as follows- A. Telomerase C. MDM2  A graduate student wants to isolate cells…

Q: examine the process of gene expression. Include the following: Explain the regulation of gene…

A: Introduction Gene Expression Is The Process Through Which Information From A Gene Is Used To Create…

Q: What strategy does a genetically encoded calcium indicator look like to allow fluorescence imaging…

A: A crucial part of astrocyte physiology and function is Ca2+ signaling. Ca2+ imaging is the most…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: Expression of ---- does not require new protein synthesis.     a.immediate early genes b. delayed…

A: We’ll answer the first question since the exact one wasn’t specified. Please submit a new question…

Q: The figure below shows 6 genes that are differentially expressed based on their specific enhancers.…

A: Enhancers are the regulatory sequences in the DNA located farther away from the transcription start…

Q: VHL is a tumor suppressor because     a. it causes cancer cells to become hypoxic     b. it…

A: Tumor is a mass or lump that results from the abnormal growth of cells in the body. A tumor…

Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

A: Translesion synthesis (TLS) is a method of overcoming stopped replication in which particular…

Q: You are looking at the results of a western blot from the lysates of cells harvested from a…

A: When you observe an increased expression of INK4-p16 in the lysates of cells harvested from a…

Q: Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had…

A: BRCA1 is a tumor suppressor gene usually expressed in breast cells. It is responsible for repairing…

Q: Targeted therapies are used in patients with a set gene expression pattern. A targeted therapy that…

A: Targeted therapies also called molecular targeted drugs for treating cancer involve drugs and other…

Q: Which of the following defects in RAS would be tumorigenic? multiple answers    A. Deletion of…

A: Ras is a nucleotide binding protein that is responsible for cell division, growth and…

Q: Hypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting…

A: DNA methylation is one of the intensely studied epigenetic modifications in mammals. The regulation…

Q: Discuss the mechanisms by which transcription factors influence the reprogramming of somatic cells…

A: Somatic cells are similar to human beings in that they develop to fulfill a specific purpose in…

Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: Which of the following associated with cancer development would you expect to be tumor promoters and…

A: Introduction: A chemical that can increase the risk of cancer by a secondary mechanism unrelated to…

Q: Which of the following is NOT a description of an epigenetic modification? A. regulatory patterns…

A: Changes in gene expression that are not produced by changes in DNA sequences but are caused by…

Q: From gene expression studies on cancer, you discovered a hypothetical gene called ABCG2 that is…

A: Transgenic approach has been proved to be very useful in studying physiological function of a…

Q: The answer did not address why most cancer mutations occur upstream of MAPK (ie. RAS (10-20% NRAS…

A: RAS protein is monomeric G protein , it will belongs in the GTPase super family of intracellular…

Q: The NFAT family is a ubiquitous family of transcription factors. a. Under resting conditions, where…

A: a. Under resting conditions, NFAT (Nuclear Factor of Activated T cells) is phosphorylated and…

Q: ct one: a The gene is turned off, but still expresses a protein product. . The gene becomes…

A: DNA methylation is associated with the silencing of gene expression.

Q: Glucocorticolds are steroid hormones that are released into the circulation and will cause changes…

A: The correct option is C

Q: One example of an oncogene is ras. Ras is a G protein that is activated when growth factors bind to…

A: Cell cycle:  It is the sequence of events by which the genome of the cells gets duplicated and the…

Q: Identify the eukaryotic level of gene regulation. Choose the correct answer below. a. Pre-…

A: INTRODUCTION Eukaryotic level of gene regulation include epigenetic, transcriptional, post…

Q: What is an example of a non Mendelian trait?

A: Non-Mendelian patterns of inheritance are also called the "complicated patterns of inheritance".…

Q: does reverse methylation affect gene expression? Select one O a The gene is tumed off, but stl…

A: Gene expression is the process by which the instructions in our DNA are converted into a functional…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: The expression of a transgene depends on its site of integration, state of differentiation of target…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.