p53 Iis an impórtant tumor suppressor gene that is activated in response to a variety of stress signals. Upon activation it induces a cell cycle arrest or cell death. Hence, loss-of-function mutations in the p53 gene are found in almost every type of cancer. How do you predict loss-of-function mutations in the DNA binding domain of the p53 protein affect its function? O It no longer will act as activator of gene expression It no longer will act as repressor of gene expression It no longer will act as activator or repressor of gene expression O It no longer will act as coactivator or corepressor
p53 Iis an impórtant tumor suppressor gene that is activated in response to a variety of stress signals. Upon activation it induces a cell cycle arrest or cell death. Hence, loss-of-function mutations in the p53 gene are found in almost every type of cancer. How do you predict loss-of-function mutations in the DNA binding domain of the p53 protein affect its function? O It no longer will act as activator of gene expression It no longer will act as repressor of gene expression It no longer will act as activator or repressor of gene expression O It no longer will act as coactivator or corepressor
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter17: Developmental Genetics
Section: Chapter Questions
Problem 8TYU: Which of the following statements about cancer is false? (a) oncogenes arise from mutations in...
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